甲状腺肿性桥本甲状腺炎。与HLA抗原无关联。
Goitrous Hashimoto's thyroiditis. Lack of association with HLA antigens.
作者信息
Fein H G, Metz S, Nikolai T F, Johnson A H, Smallridge R C
出版信息
Mol Biol Med. 1986 Apr;3(2):195-9.
PMID:3461235
Abstract
We studied HLA antigen frequency in 54 carefully selected patients with goitrous Hashimoto's thyroiditis. All had an appropriate clinical course, positive family history, antithyroid antibodies and/or a needle biopsy indicating chronic lymphocytic thyroiditis. We found no statistically significant association with any HLA-A, -B, -C or DR specificity.
摘要
我们研究了54例精心挑选的桥本甲状腺炎伴甲状腺肿患者的HLA抗原频率。所有患者都有恰当的临床病程、阳性家族史、抗甲状腺抗体和/或针吸活检提示慢性淋巴细胞性甲状腺炎。我们发现与任何HLA - A、- B、- C或DR特异性均无统计学上的显著关联。
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