IRCCS San Raffaele, Rome, Italy.
Institute of Heart Diseases, Wrocław Medical University, Wrocław, Poland.
Eur J Heart Fail. 2021 Nov;23(11):1806-1818. doi: 10.1002/ejhf.2356.
Patients with heart failure (HF) who contract SARS-CoV-2 infection are at a higher risk of cardiovascular and non-cardiovascular morbidity and mortality. Regardless of therapeutic attempts in COVID-19, vaccination remains the most promising global approach at present for controlling this disease. There are several concerns and misconceptions regarding the clinical indications, optimal mode of delivery, safety and efficacy of COVID-19 vaccines for patients with HF. This document provides guidance to all healthcare professionals regarding the implementation of a COVID-19 vaccination scheme in patients with HF. COVID-19 vaccination is indicated in all patients with HF, including those who are immunocompromised (e.g. after heart transplantation receiving immunosuppressive therapy) and with frailty syndrome. It is preferable to vaccinate against COVID-19 patients with HF in an optimal clinical state, which would include clinical stability, adequate hydration and nutrition, optimized treatment of HF and other comorbidities (including iron deficiency), but corrective measures should not be allowed to delay vaccination. Patients with HF who have been vaccinated against COVID-19 need to continue precautionary measures, including the use of facemasks, hand hygiene and social distancing. Knowledge on strategies preventing SARS-CoV-2 infection (including the COVID-19 vaccination) should be included in the comprehensive educational programmes delivered to patients with HF.
患有心力衰竭 (HF) 的患者感染 SARS-CoV-2 后,心血管和非心血管发病率和死亡率的风险更高。无论在 COVID-19 治疗方面做出何种尝试,疫苗接种目前仍是控制这种疾病的最有希望的全球方法。对于 HF 患者,COVID-19 疫苗的临床适应证、最佳接种方式、安全性和有效性存在一些担忧和误解。本文件为所有医疗保健专业人员提供了 HF 患者实施 COVID-19 疫苗接种计划的指南。所有 HF 患者均推荐接种 COVID-19 疫苗,包括免疫功能低下的患者(例如,接受免疫抑制治疗的心脏移植后)和衰弱综合征患者。最好在 HF 患者处于最佳临床状态下接种 COVID-19 疫苗,这将包括临床稳定、充分的水合和营养、HF 及其他合并症(包括缺铁)的优化治疗,但不应因纠正措施而推迟接种。已接种 COVID-19 疫苗的 HF 患者需要继续采取预防措施,包括使用口罩、手部卫生和保持社交距离。预防 SARS-CoV-2 感染(包括 COVID-19 疫苗接种)的策略知识应包含在向 HF 患者提供的综合教育计划中。