Dept of Pathology, Marie Lannelongue Hospital, Le Plessis Robinson, France.
Dept of Pathology, Marie Lannelongue Hospital, Le Plessis Robinson, France
Eur Respir Rev. 2021 Oct 5;30(162). doi: 10.1183/16000617.0309-2020. Print 2021 Dec 31.
The diagnosis of a mediastinal mass may be challenging for clinicians, since lesions arising within the mediastinum include a variety of disease entities, frequently requiring a multidisciplinary approach. Age and sex represent important information, which need to be integrated with imaging and laboratory findings. In addition, the location of the mediastinal lesion is fundamental; indeed, we propose to illustrate mediastinal diseases based on the compartment of origin. We consider that this structured approach may serve as hint to the diagnostic modalities and management of mediastinal diseases. In this review, we present primary mediastinal tumours in the evolving context of new diagnostic and therapeutic tools, with recently described entities, based on our own experience with >900 cases encountered in the past 10 years.
纵隔肿块的诊断对临床医生来说可能具有挑战性，因为纵隔内的病变包括多种疾病实体，通常需要多学科方法。年龄和性别是重要的信息，需要与影像学和实验室发现相结合。此外，纵隔病变的位置是至关重要的；事实上，我们建议根据起源部位来阐述纵隔疾病。我们认为，这种结构化的方法可以作为纵隔疾病的诊断方式和治疗的提示。在这篇综述中，我们根据过去 10 年中遇到的 >900 例病例的经验，在新的诊断和治疗工具的不断发展的背景下，介绍了原发性纵隔肿瘤和最近描述的实体。
