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本文引用的文献

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A clinical guideline on Dientamoeba fragilis infections.关于脆弱双核阿米巴感染的临床指南。
Parasitology. 2019 Aug;146(9):1131-1139. doi: 10.1017/S0031182018001385. Epub 2018 Aug 31.
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Description of Dientamoeba fragilis cyst and precystic forms from human samples.来自人体样本的脆弱双核阿米巴包囊和前包囊形态的描述。
J Clin Microbiol. 2014 Jul;52(7):2680-3. doi: 10.1128/JCM.00813-14. Epub 2014 May 7.
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Current treatment options for Dientamoeba fragilis infections.脆弱双核阿米巴感染的当前治疗选择。
Int J Parasitol Drugs Drug Resist. 2012 Sep 3;2:204-15. doi: 10.1016/j.ijpddr.2012.08.002. eCollection 2012 Dec.
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Budd-Chiari syndrome due to giant hydatid cyst: a case report and brief literature review.巨大包虫囊肿所致布加综合征:一例报告并文献简要回顾
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Eosinophilia and thrombosis in parasitic diseases: an overview.寄生虫病中的嗜酸性粒细胞增多与血栓形成:概述。
Clin Appl Thromb Hemost. 2011 Feb;17(1):33-8. doi: 10.1177/1076029609348314. Epub 2009 Oct 14.
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Budd-Chiari syndrome: etiology, pathogenesis and diagnosis.布加综合征:病因、发病机制与诊断
World J Gastroenterol. 2007 May 21;13(19):2693-6. doi: 10.3748/wjg.v13.i19.2693.
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Eosinophils are a major intravascular location for tissue factor storage and exposure.嗜酸性粒细胞是组织因子储存和暴露的主要血管内场所。
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8
Budd-Chiari syndrome in a patient heterozygous for the G20210A mutation of the prothrombin gene.一名凝血酶原基因G20210A突变杂合子患者的布加综合征
Thromb Haemost. 1998 Feb;79(2):445-6.
9
Spontaneous erythroid colony formation as the clue to an underlying myeloproliferative disorder in patients with Budd-Chiari syndrome or portal vein thrombosis.自发性红系集落形成作为布加综合征或门静脉血栓形成患者潜在骨髓增殖性疾病的线索。
Semin Thromb Hemost. 1997;23(5):411-8. doi: 10.1055/s-2007-996117.
10
Expression, purification, and characterization of the recombinant proform of eosinophil granule major basic protein.嗜酸性粒细胞颗粒主要碱性蛋白重组前体形式的表达、纯化及特性分析
J Immunol. 1995 Aug 1;155(3):1472-80.

布加综合征患者的一个新病因

A Novel Culprit in a Patient with Budd-Chiari Syndrome.

作者信息

Polman Jeremy, Reddy Sainandan, Williams Aaron C, DeWitt Aaron

机构信息

Internal Medicine Residency Program, Baton Rouge General, Baton Rouge, Louisiana, USA.

出版信息

Case Rep Gastroenterol. 2021 May 25;15(2):470-474. doi: 10.1159/000516210. eCollection 2021 May-Aug.

DOI:10.1159/000516210
PMID:34616241
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8454246/
Abstract

Budd-Chiari syndrome (BCS) is an uncommon illness that is characterized by obstruction of hepatic venous outflow. Patients typically present with nausea, vomiting, and abdominal pain, which can further progress into signs associated with liver failure, including jaundice, encephalopathy, and coagulopathy. The most common causes of BCS include pathologies that induce portal vein thrombosis, such as myeloproliferative disorders, malignancy, and acquired hypercoagulable states. In this case report, a patient who presented with abdominal pain and distention is diagnosed with BCS caused by an unusual etiology. He was found to have significant eosinophilia, prompting additional evaluation for parasitic infections. Using stool diagnostics/studies, he was found to have trophozoites. The patient was treated with enoxaparin, warfarin, and metronidazole with a resolution of his symptoms. This case outlines a novel cause of BCS as well as the proposed mechanism of induction of BCS.

摘要

布加综合征(BCS)是一种罕见疾病,其特征为肝静脉流出道梗阻。患者通常表现为恶心、呕吐和腹痛,这些症状可进一步发展为与肝衰竭相关的体征,包括黄疸、脑病和凝血功能障碍。BCS最常见的病因包括导致门静脉血栓形成的病变,如骨髓增殖性疾病、恶性肿瘤和获得性高凝状态。在本病例报告中,一名出现腹痛和腹胀的患者被诊断为由不寻常病因引起的BCS。发现他有明显的嗜酸性粒细胞增多症,促使对寄生虫感染进行进一步评估。通过粪便诊断/检查,发现他有滋养体。该患者接受了依诺肝素、华法林和甲硝唑治疗,症状得到缓解。本病例概述了BCS的一种新病因以及BCS的诱发机制。