Volkert Jana, Taubner Svenja, Barkauskiene Rasa, Mestre Jose M, Sales Célia M D, Thiele Vanessa, Saliba Andrea, Protić Sonja, Adler Asta, Conejo-Cerón Sonia, Di Giacomo Dina, Ioannou Yianna, Moreno-Peral Patricia, Vieira Filipa Mucha, Mota Catarina Pinheiro, Raleva Marija, Rangel Santos Henriques Margarida Isabel, Røssberg Jan Ivar, Schmidt Stefanie J, Perdih Tjasa Stepisnik, Ulberg Randi, Heinonen Erkki
Department of Psychology, MSB Medical School Berlin, Berlin, Germany.
Institute of Psychosocial Prevention, University of Heidelberg, Heidelberg, Germany.
Front Psychol. 2021 Sep 20;12:703095. doi: 10.3389/fpsyg.2021.703095. eCollection 2021.
Personality disorders (PDs) are a severe health issue already prevalent among adolescents and young adults. Early detection and intervention offer the opportunity to reduce disease burden and chronicity of symptoms and to enhance long-term functional outcomes. While psychological treatments for PDs have been shown to be effective for young people, the mediators and specific change mechanisms of treatment are still unclear. As part of the "European Network of Individualized Psychotherapy Treatment of Young People with Mental Disorders" (TREATme), funded by the European Cooperation in Science and Technology (COST), we will conduct a systematic review to summarize the existing knowledge on mediators of treatment outcome and theories of change in psychotherapy for young people with personality disorders. In particular, we will evaluate whether mediators appear to be common or specific to particular age groups, treatment models, or outcome domains (e.g., psychosocial functioning, life quality, and adverse treatment effects). We will follow the reporting guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement recommendations. Electronic databases (PubMed and PsycINFO) have been systematically searched for prospective, longitudinal, and case-control designs of psychological treatment studies, which examine mediators published in English. Participants will be young people between 10 and 30years of age who suffer from subclinical personality symptoms or have a personality disorder diagnosis and receive an intervention that aims at preventing, ameliorating, and/or treating psychological problems. The results will be published in a peer-reviewed journal and at conference presentations and will be shared with relevant stakeholder groups. The data set will be made available to other research groups following recommendations of the open science initiative. Databases with the systematic search will be made openly available following open science initiatives. The review has been registered in PROSPERO (evaluation is pending, registration number ID 248959). This review will deliver a comprehensive overview on the empirical basis to contribute to the further development of psychological treatments for young people with personality disorders.
人格障碍（PDs）是一个严重的健康问题，在青少年和青年中已经很普遍。早期发现和干预提供了减轻疾病负担和症状慢性化以及改善长期功能结局的机会。虽然针对人格障碍的心理治疗已被证明对年轻人有效，但治疗的中介因素和具体改变机制仍不清楚。作为由欧洲科技合作组织（COST）资助的“欧洲青少年精神障碍个体化心理治疗网络”（TREATme）的一部分，我们将进行一项系统综述，以总结关于人格障碍青少年心理治疗结果的中介因素和改变理论的现有知识。特别是，我们将评估中介因素是否似乎对特定年龄组、治疗模式或结局领域（如心理社会功能、生活质量和不良治疗效果）是常见的还是特定的。我们将遵循系统评价和荟萃分析的首选报告项目（PRISMA）声明建议的报告指南。我们已经系统地搜索了电子数据库（PubMed和PsycINFO），以查找心理治疗研究的前瞻性、纵向和病例对照设计，这些研究考察了用英文发表的中介因素。参与者将是年龄在10至30岁之间、患有亚临床人格症状或有人格障碍诊断并接受旨在预防、改善和/或治疗心理问题的干预措施的年轻人。结果将发表在同行评审期刊上并在会议上展示，并将与相关利益相关者群体分享。根据开放科学倡议的建议，数据集将提供给其他研究小组。遵循开放科学倡议，将公开提供系统搜索的数据库。该综述已在PROSPERO注册（评估正在进行中，注册号ID 248959）。本综述将在实证基础上提供全面概述，以促进针对人格障碍青少年心理治疗的进一步发展。
