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Ir J Med Sci. 2022 Aug;191(4):1849-1853. doi: 10.1007/s11845-021-02796-9. Epub 2021 Oct 6.
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Empiric treatment for peritonsillar abscess: A single-center experience with medical therapy alone.经验性治疗扁桃体周脓肿:单中心单纯药物治疗的经验。
Am J Otolaryngol. 2021 Jul-Aug;42(4):102954. doi: 10.1016/j.amjoto.2021.102954. Epub 2021 Feb 5.
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Antibiotics in treatment of peritonsillar infection: clindamycin versus penicillin.抗生素治疗扁桃体周围感染:克林霉素与青霉素。
J Laryngol Otol. 2021 Jan;135(1):64-69. doi: 10.1017/S002221512100013X. Epub 2021 Jan 22.
4
Risk of internal carotid injury due to peritonsillar abscess drainage.扁桃体周围脓肿切开引流致颈内动脉损伤风险。
Auris Nasus Larynx. 2020 Dec;47(6):1027-1032. doi: 10.1016/j.anl.2020.06.001. Epub 2020 Jun 21.
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Medical Intervention Alone vs Surgical Drainage for Treatment of Peritonsillar Abscess: A Systematic Review and Meta-analysis.单纯医学干预与手术引流治疗扁桃体周脓肿:系统评价和荟萃分析。
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6
Comparison of needle aspiration versus incision and drainage under local anaesthesia for the initial treatment of peritonsillar abscess.局麻下经皮穿刺抽脓与切开引流术治疗扁桃体周围脓肿的疗效比较。
Eur Arch Otorhinolaryngol. 2019 Sep;276(9):2595-2601. doi: 10.1007/s00405-019-05542-1. Epub 2019 Jul 12.
7
Infections of the Neck.颈部感染
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8
Infections of the Oropharynx.口咽感染
Emerg Med Clin North Am. 2019 Feb;37(1):69-80. doi: 10.1016/j.emc.2018.09.002.
9
Peritonsillar abscess: A retrospective case series of 1773 patients.扁桃体周脓肿:1773例患者的回顾性病例系列研究
Clin Otolaryngol. 2018 Jun;43(3):940-944. doi: 10.1111/coa.13070. Epub 2018 Feb 19.
10
Comparison of Medical Therapy Alone to Medical Therapy with Surgical Treatment of Peritonsillar Abscess.单纯药物治疗与药物联合手术治疗扁桃体周脓肿的比较。
Otolaryngol Head Neck Surg. 2018 Feb;158(2):280-286. doi: 10.1177/0194599817739277. Epub 2017 Nov 7.

有脓处,即排脓处:601 例成人扁桃体周脓肿病例回顾。

Ubi pus, ibi evacua: a review of 601 peritonsillar abscess adult cases.

机构信息

2nd Otolaryngology Department, School of Medicine, "Attikon" University Hospital, National & Kapodistrian University of Athens, Rimini 1 Chaidari, 124 62, Athens, Greece.

Department of Infomatics, University of Peiraeus, Peiraeus, Greece.

出版信息

Ir J Med Sci. 2022 Aug;191(4):1849-1853. doi: 10.1007/s11845-021-02796-9. Epub 2021 Oct 6.

DOI:10.1007/s11845-021-02796-9
PMID:34617243
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8494509/
Abstract

BACKGROUND

Peritonsillar abscess (PTA) is the most common deep neck infection, occurring as a consequence of bacterial acute tonsillitis or as a result of infection of the Weber glands, with frequent and life-threatening complications.

AIM

To investigate several factors associated with complications and worse prognosis, such as defining the method of surgical drainage and treatment of a PTA which remains an area of controversy in the literature METHODS: The purpose of this retrospective study is to examine the epidemiological, clinical, and laboratory findings of 601 adult patients and to discuss them along with their treatment plan.

RESULTS

Pharyngalgia was the most common reported symptom, followed by trismus, odynophagia, fever, hot potato voice, malaise, and cervical lymphadenopathy. Sixty-eight patients developed complications. Streptococcus species were the most common pathogens. A statistically significant difference was found in days of hospitalization, WBC and CRP levels, age, and the pre-existing systemic diseases between patients with and without complications. A comparison of patients treated with intravenous and oral antibiotics revealed no statistically significant difference.

CONCLUSION

Οver 10% of PTA cases may develop complications, the most common of which is extension into deep neck spaces. Comorbid conditions increase the risk of complications. Despite the wide range of treatment strategies, incision and drainage remain the cornerstone of surgical treatment. In patients with no comorbidities, intravenous antibiotics appear to have no advantage over oral antibiotics.

摘要

背景

扁桃体周脓肿(PTA)是最常见的深部颈感染,是细菌性急性扁桃体炎的后果,或是韦氏腺感染的结果,常伴有频繁且危及生命的并发症。

目的

研究与并发症和预后不良相关的多种因素,例如确定手术引流方法和 PTA 的治疗方法,这在文献中仍然存在争议。

方法

本回顾性研究旨在检查 601 例成年患者的流行病学、临床和实验室发现,并结合他们的治疗计划进行讨论。

结果

咽痛是最常见的报告症状,其次是牙关紧闭、吞咽困难、发热、声嘶、不适和颈部淋巴结肿大。68 例患者发生并发症。链球菌属是最常见的病原体。有并发症和无并发症患者的住院天数、白细胞和 C 反应蛋白水平、年龄和既往全身性疾病存在统计学显著差异。静脉和口服抗生素治疗的患者比较无统计学显著差异。

结论

超过 10%的 PTA 病例可能发生并发症,最常见的并发症是向深部颈间隙扩展。合并症增加了并发症的风险。尽管治疗策略广泛,但切开引流仍然是手术治疗的基石。在无合并症的患者中,静脉用抗生素似乎没有优于口服抗生素。