Non-communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj, Iran.
Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran.
Clin Nutr ESPEN. 2021 Oct;45:66-74. doi: 10.1016/j.clnesp.2021.07.028. Epub 2021 Aug 18.
The present study aimed to review and perform a meta-analysis summarizing the available evidence on the association between red meat consumption and obesity.
A computerized search strategy was performed up to Feb 9, 2020. PubMed, Scopus, and web of science were used to conduct a comprehensive search for all relevant publications. The quality of the included articles was determined by using the Newcastle-Ottawa Scale. A random-effects model was conducted for analysis of the included cross-sectional studies. In the case of significant heterogeneity, subgroup analyses were conducted to explore possible sources of inter-study heterogeneity.
In the overall pooled estimate of 3 studies, it was shown that red meat consumption was not associated with overweight (pooled effect size: 1.19, 95% CI: 0.97-1.46, p = 0.099). The results from combining 7 studies showed a non-significant association between red meat intake and obesity (pooled effect size: 1.16, 95% CI: 0.93-1.44, p = 0.199) with significant heterogeneity among studies (I = 87.3%, p < 0.0001).
In conclusion, results extend the evidence that red meat consumption was not associated with the risk of overweight as well as no association between total meat consumption and obesity.
本研究旨在回顾并进行荟萃分析，总结有关红肉类消费与肥胖之间关联的现有证据。
截至 2020 年 2 月 9 日，我们采用计算机检索策略检索了所有相关文献。使用 PubMed、Scopus 和 web of science 全面检索了所有相关出版物。使用纽卡斯尔-渥太华量表确定纳入文章的质量。对纳入的横断面研究进行了随机效应模型分析。如果存在显著的异质性，则进行亚组分析以探讨研究间异质性的可能来源。
在对 3 项研究的总体汇总估计中，表明红肉类消费与超重无关（汇总效应大小：1.19，95%CI：0.97-1.46，p=0.099）。对 7 项研究的结果进行合并表明，红肉类摄入与肥胖之间无显著关联（汇总效应大小：1.16，95%CI：0.93-1.44，p=0.199），且研究间存在显著异质性（I=87.3%，p<0.0001）。
总之，结果扩展了证据，表明红肉类消费与超重风险无关，总肉类消费与肥胖之间也没有关联。
