Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway; Department of Cardiology, St. Olav Hospital/Trondheim University Hospital, Trondheim, Norway.
Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway.
Ultrasound Med Biol. 2021 Dec;47(12):3501-3513. doi: 10.1016/j.ultrasmedbio.2021.08.021. Epub 2021 Oct 5.
This study examines the feasibility of blood speckle tracking for vector flow imaging in healthy adults and describes the physiologic flow pattern and vortex formation in relation to the wall motion in the left ventricle. The study included 21 healthy volunteers and quantified and visualized flow patterns with high temporal resolution down to a depth of 10-12 cm without the use of contrast agents. Intraventricular flow seems to originate during the isovolumetric relaxation with a propagation of blood from base to apex. With the E-wave, rapid inflow and vortex formation occurred on both sides of the valve basally. During diastasis the flow gathers in a large vortex before the pattern from the E-wave repeats during the A-wave. In isovolumetric contraction, the flow again gathers in a large vortex that seems to facilitate the flow out in the aorta during systole. No signs of a persistent systolic vortex were visualized. The geometry of the left ventricle and the movement of the AV-plane is important in creating vortices that are favorable for the blood flow and facilitate outflow. The quantitative measurements are in concordance with these findings, but the clinical interpretation must be evaluated in future clinical studies.
本研究旨在探讨血液斑点追踪技术在健康成年人中向量血流成像的可行性，并描述与左心室壁运动相关的生理流动模式和涡流形成。该研究纳入了 21 名健康志愿者，使用高时间分辨率技术，在不使用对比剂的情况下，对 10-12cm 深处的血流模式进行量化和可视化。室内心脏血流似乎起源于等容舒张期，血液从底部向顶部传播。在 E 波期间，瓣膜底部两侧会迅速出现血液流入和涡流形成。在舒张期，血流会聚集在一个大的涡流中，然后在 A 波期间再次出现 E 波的模式。在等容收缩期，血流再次聚集在一个大的涡流中，这似乎有利于在收缩期将血流排出主动脉。未观察到持续的收缩期涡流的迹象。左心室的几何形状和房室平面的运动对于产生有利于血流并促进流出的涡流非常重要。定量测量结果与这些发现一致，但临床解释必须在未来的临床研究中进行评估。
