Suppr超能文献

我们正在取得进展吗?一项随机对照试验,该试验采用由心理学家支持的基于网络的认知行为疗法干预措施,以减少新兴成年人的焦虑和有害饮酒行为。

Are we making Inroads? A randomized controlled trial of a psychologist-supported, web-based, cognitive behavioral therapy intervention to reduce anxiety and hazardous alcohol use among emerging adults.

作者信息

Stapinski Lexine A, Prior Katrina, Newton Nicola C, Biswas Raaj Kishore, Kelly Erin, Deady Mark, Lees Briana, Teesson Maree, Baillie Andrew J

机构信息

The Matilda Centre for Research in Mental Health and Substance Use, Sydney Medical School, The University of Sydney, Camperdown, NSW 2006, Australia.

Transport and Road Safety (TARS) Research Centre, School of Aviation, University of New South Wales, Sydney 2052, Australia.

出版信息

EClinicalMedicine. 2021 Aug 8;39:101048. doi: 10.1016/j.eclinm.2021.101048. eCollection 2021 Sep.

Abstract

BACKGROUND

Anxiety and alcohol use disorders are common and disabling conditions that people typically endure for many years before accessing treatment. The link between anxiety and alcohol use is well-established, with these issues commonly emerging and/or escalating during emerging adulthood. This randomized controlled trial evaluated a psychologist-supported, web-based intervention, designed with and for emerging adults, that aims to promote adaptive coping strategies, and prevent anxiety and alcohol use from progressing to chronic, mutually-reinforcing disorders.

METHODS

Between December 2017 and September 2018, 123 emerging adults (aged 17-24) reporting anxiety symptoms and hazardous alcohol use were randomized to receive the or control (assessment plus alcohol information) intervention. The program combined five web-based cognitive behavioral therapy modules with weekly psychologist support via email/phone. Primary outcomes were alcohol consumption, severity of alcohol-related consequences, and general anxiety symptoms, assessed at baseline, 2 and 6-months post-baseline. Secondary outcomes included hazardous alcohol use and social anxiety Trial Registration: Prospectively registered in the Australian New Zealand Clinical Trials Registry, ACTRN12617001609347.

FINDINGS

Alcohol consumption and associated consequences reduced in both groups, with the group reporting greater alcohol reductions by 6-month follow-up (mean difference -0.74, 95% CI: -1.47 to -0.01,  = 0.24). Relative to controls, hazardous alcohol use reduced among participants at both follow-ups (2-month mean difference -2.14, 95% CI: -4.06 to -0.22). participants also reported reduced symptoms of general (mean difference -3.06, 95% CI: -4.97 to -1.15,  = 0.88) and social anxiety (mean difference -3.21, 95% CI: -6.34 to -0.07,  = 0.32) at 2-month follow-up, with improvements in social anxiety sustained at 6-months.

INTERPRETATION

The program demonstrated beneficial effects on alcohol consumption, hazardous alcohol use, and anxiety symptoms. The web-based format is aligned with youth treatment preferences and can be delivered at scale to achieve wide dissemination and reduce the significant burden associated with these chronic, mutually reinforcing conditions.

FUNDING

Australian Rotary Health, Australian National Health and Medical Research Council.

摘要

背景

焦虑症和酒精使用障碍是常见的致残性疾病,人们通常在多年后才会寻求治疗。焦虑与酒精使用之间的联系已得到充分证实,这些问题在成年初期通常会出现和/或加剧。这项随机对照试验评估了一种由心理学家支持的、基于网络的干预措施,该措施是为成年初期人群设计并针对他们的,旨在促进适应性应对策略,并防止焦虑和酒精使用发展为慢性、相互强化的疾病。

方法

在2017年12月至2018年9月期间,123名报告有焦虑症状和危险饮酒行为的成年初期人群(年龄在17 - 24岁之间)被随机分配接受干预或对照(评估加酒精信息)干预。干预方案将五个基于网络的认知行为疗法模块与通过电子邮件/电话提供的每周一次的心理学家支持相结合。主要结局指标为酒精消费量、与酒精相关后果的严重程度以及一般焦虑症状,在基线、基线后2个月和6个月时进行评估。次要结局指标包括危险饮酒行为和社交焦虑。试验注册:在澳大利亚新西兰临床试验注册中心进行前瞻性注册,ACTRN12617001609347。

研究结果

两组的酒精消费量及相关后果均有所减少,干预组在6个月随访时报告酒精减少量更大(平均差值 -0.74,95%置信区间:-1.47至 -0.01,P = 0.24)。与对照组相比,干预组参与者在两次随访时危险饮酒行为均有所减少(2个月时平均差值 -2.14,95%置信区间:-4.06至 -0.22)。干预组参与者在2个月随访时还报告一般焦虑症状(平均差值 -3.06,95%置信区间:-4.97至 -1.15,P = 0.88)和社交焦虑症状(平均差值 -3.21,95%置信区间:-6.34至 -0.07,P = 0.32)有所减轻,社交焦虑症状在6个月时持续改善。

解读

该干预方案对酒精消费、危险饮酒行为和焦虑症状显示出有益效果。基于网络的形式符合年轻人的治疗偏好,可以大规模推广以实现广泛传播,并减轻与这些慢性、相互强化疾病相关的重大负担。

资助

澳大利亚扶轮健康组织、澳大利亚国家卫生与医学研究委员会。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cde7/8478683/e010a981b0c4/gr1.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验