Department of Psychology, Maynooth University; Assisting Living and Learning Institute, Maynooth University.
Department of Psychology, Maynooth University.
Mult Scler Relat Disord. 2021 Nov;56:103293. doi: 10.1016/j.msard.2021.103293. Epub 2021 Oct 1.
Multiple Sclerosis (MS) is a highly variable condition characterised by uncertainty of disease course which can make formation of expectations about the future difficult. This systematic review aimed to examine associations between expectations, or Future Oriented Cognitions (FOCs), and Quality of Life (QOL) in people with MS (PwMS).
Following PRISMA guidelines, literature up to October 2019 was searched using Medline, EMBASE, PsycINFO and Web of Science. Quantitative studies that investigated relationships between FOCs and QOL in PwMS (assessed using a standardised QOL assessment) were considered for inclusion. After data extraction, results were analysed using narrative synthesis, focusing on the valence of FOCs (positive, negative, unvalenced). Quality appraisal was conducted using the Mixed Methods Appraisal Tool (MMAT). All stages of the review were patient-led by a person with MS.
A total of 13 studies met the review inclusion criteria, with a combined sample size of 4,179. Of these studies, 11 involved measures of positive FOCs, most commonly self-efficacy, one measured a negative FOC, with one FOC unclassified. Nine studies found significant associations between QOL and self-efficacy. Although other positively valenced constructs were less frequently reported, significant associations with higher QOL were also evidenced.
Identifying ways to foster positive FOCs, particularly self-efficacy, may have beneficial effects on QOL. More research is needed to understand the impacts of negative FOCs on QOL to determine whether these processes could be meaningfully targeted in interventions.
多发性硬化症（MS）是一种高度可变的疾病，其疾病进程不确定，这使得对未来的期望难以形成。本系统评价旨在研究多发性硬化症患者（PwMS）的期望或未来定向认知（FOC）与生活质量（QOL）之间的关系。
根据 PRISMA 指南，使用 Medline、EMBASE、PsycINFO 和 Web of Science 对截至 2019 年 10 月的文献进行了搜索。纳入了研究 FOCs 与 PwMS 中 QOL 之间关系的定量研究（使用标准化 QOL 评估进行评估）。在数据提取后，使用叙述性综合分析方法分析结果，重点关注 FOCs 的正负性（正性、负性、中性）。使用混合方法评估工具（MMAT）进行质量评估。整个审查过程均由一位多发性硬化症患者主导。
共有 13 项研究符合纳入标准，合并样本量为 4179 人。其中，11 项研究涉及正性 FOCs 的测量，最常见的是自我效能，一项研究测量了负性 FOCs，一项研究未对 FOCs 进行分类。9 项研究发现 QOL 与自我效能之间存在显著关联。尽管其他正向评价结构报告较少，但也有证据表明它们与更高的 QOL 显著相关。
识别培养正性 FOCs 的方法，特别是自我效能，可能对 QOL 有益。需要进一步研究以了解负性 FOCs 对 QOL 的影响，以确定这些过程是否可以在干预措施中得到有意义的针对。
