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方法学研究:多发性硬化症患者时间观评分与生活质量的关系。

Methodological Investigation of Time Perspective Scoring and Quality of Life among Individuals with Multiple Sclerosis.

机构信息

Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.

出版信息

Int J Environ Res Public Health. 2022 Apr 21;19(9):5038. doi: 10.3390/ijerph19095038.

DOI:10.3390/ijerph19095038
PMID:35564432
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9102034/
Abstract

Achieving and maintaining a high quality of life following the diagnosis of chronic illness has a positive impact on the experience of illness, including delayed disease progression and fewer relapses. Time perspective has shown promising relationships with quality of life, though studies using the construct in samples with chronic illness are sparse and methodologically heterogeneous. Participants ( = 123) were diagnosed with relapsing-remitting multiple sclerosis at least five years prior to enrollment and were beginning a new disease modifying therapy (DMT). The Zimbardo Time Perspective Inventory (ZTPI) and the World Health Organization Quality of Life (WHOQoL-100) assessment were administered at baseline and the WHOQoL-100 was administered six-weeks after starting the new DMT. This study investigated the utility of three common methods of scoring and interpreting ZTPI (balanced vs. deviation-from-balanced, categorical, and continuous scores) to predict change in quality of life. Independent sample -tests revealed no difference in quality of life for balanced vs. deviation-from-balanced. One-way ANOVA revealed no difference in quality of life across time perspective categories. Linear regression analysis found that past-negative scores predicted decreases in all quality of life domains as well as overall score while present hedonistic scores predicted increases in psychological and overall quality of life.

摘要

在诊断出慢性疾病后,实现并保持高质量的生活对疾病体验有积极影响,包括延缓疾病进展和减少复发。时间视角与生活质量之间已经显示出有希望的关系,但在患有慢性疾病的样本中使用该结构的研究很少,且方法学上存在差异。参与者(n=123)在入组前至少五年被诊断为复发缓解型多发性硬化症,并开始新的疾病修正治疗(DMT)。在基线时进行了 Zimbardo 时间视角量表(ZTPI)和世界卫生组织生活质量(WHOQoL-100)评估,在开始新的 DMT 后六周进行了 WHOQoL-100 评估。本研究调查了三种常见的 ZTPI 评分和解释方法(平衡与非平衡、分类和连续评分)预测生活质量变化的效用。独立样本 t 检验显示,平衡与非平衡之间的生活质量没有差异。单因素方差分析显示,时间视角类别之间的生活质量没有差异。线性回归分析发现,过去消极分数预测所有生活质量领域以及整体分数的下降,而现在享乐主义分数预测心理和整体生活质量的增加。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4fd/9102034/7b5d499e9743/ijerph-19-05038-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4fd/9102034/7b5d499e9743/ijerph-19-05038-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4fd/9102034/7b5d499e9743/ijerph-19-05038-g001.jpg

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本文引用的文献

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J Pers Med. 2021 Nov 17;11(11):1218. doi: 10.3390/jpm11111218.
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期待和面向未来的认知在多发性硬化症患者生活质量中的作用:系统评价。
Mult Scler Relat Disord. 2021 Nov;56:103293. doi: 10.1016/j.msard.2021.103293. Epub 2021 Oct 1.
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BMC Neurol. 2021 May 11;21(1):193. doi: 10.1186/s12883-021-02213-9.
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Psychiatry Res. 2020 Nov;293:113383. doi: 10.1016/j.psychres.2020.113383. Epub 2020 Aug 18.
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