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[伴有慢性扁桃体炎的SAPHO综合征:一例报告及文献复习]

[SAPHO syndrome with chronic tonsillitis: a case report and literature review].

作者信息

Jia Hui, Li Yong, Liu Zengping, Guo Yufen

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2021 Oct;35(10):944-947. doi: 10.13201/j.issn.2096-7993.2021.10.018.

Abstract

SAPHO syndrome is a rare disease which affects the bones, joints, and skin. It is often misdiagnosed and treated mistakenly because of various clinical manifestations and general lack of awareness about the disease. The pathogenesis is inadequately understood, as a result, current therapy is empirical and aimed to control inflammatory process and alleviate pain. This paper summarizes the clinical manifestations and diagnosis and treatment scheme of SAPHO syndrome, and presents a case of patient with SAPHO syndrome who was treated in our department for bilateral tonsillectomy due to repeated pharyngalgia and fever for 10 years. Interestingly, the patient is getting better after the operation. The case is reported so as to provide reference for the diagnosis and treatment of SAPHO syndrome.

摘要

滑膜炎、痤疮、脓疱病、骨肥厚、骨炎综合征(SAPHO综合征)是一种累及骨骼、关节和皮肤的罕见疾病。由于其临床表现多样且普遍缺乏对该疾病的认识,它常常被误诊和误治。其发病机制尚未完全明确,因此,目前的治疗是经验性的,旨在控制炎症过程并减轻疼痛。本文总结了SAPHO综合征的临床表现、诊断和治疗方案,并介绍了1例在我科因反复咽痛、发热10年而行双侧扁桃体切除术的SAPHO综合征患者。有趣的是,该患者术后病情好转。报道此病例旨在为SAPHO综合征的诊断和治疗提供参考。

相似文献

1
[SAPHO syndrome with chronic tonsillitis: a case report and literature review].[伴有慢性扁桃体炎的SAPHO综合征:一例报告及文献复习]
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2021 Oct;35(10):944-947. doi: 10.13201/j.issn.2096-7993.2021.10.018.
10
[SAPHO syndrome--clinical report].
Acta Reumatol Port. 2006 Apr-Jun;31(2):175-80.

本文引用的文献

1
Imaging features in patients with SAPHO/CRMO: a pictorial review.SAPHO/CRMO患者的影像学特征:图文综述
Jpn J Radiol. 2020 Jul;38(7):622-629. doi: 10.1007/s11604-020-00953-1. Epub 2020 Apr 30.
2
Biologics in SAPHO syndrome: A systematic review.SAPHO 综合征中的生物制剂:系统评价。
Semin Arthritis Rheum. 2019 Feb;48(4):618-625. doi: 10.1016/j.semarthrit.2018.04.003. Epub 2018 Apr 17.
3
SAPHO Syndrome Masquerading as Metastatic Breast Cancer.伪装成转移性乳腺癌的SAPHO综合征。
Case Rep Rheumatol. 2018 Mar 20;2018:3168452. doi: 10.1155/2018/3168452. eCollection 2018.
5
Clinical heterogeneity of SAPHO syndrome: Challenge of diagnosis.SAPHO综合征的临床异质性:诊断挑战
Mod Rheumatol. 2018 May;28(3):432-434. doi: 10.1080/14397595.2017.1416733. Epub 2018 Jan 5.
10
SAPHO syndrome: a review.滑膜炎、痤疮、脓疱病、骨肥厚、骨炎综合征:综述
J Child Orthop. 2015 Feb;9(1):19-27. doi: 10.1007/s11832-014-0627-7. Epub 2015 Jan 14.

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