Jia Hui, Li Yong, Liu Zengping, Guo Yufen
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2021 Oct;35(10):944-947. doi: 10.13201/j.issn.2096-7993.2021.10.018.
SAPHO syndrome is a rare disease which affects the bones, joints, and skin. It is often misdiagnosed and treated mistakenly because of various clinical manifestations and general lack of awareness about the disease. The pathogenesis is inadequately understood, as a result, current therapy is empirical and aimed to control inflammatory process and alleviate pain. This paper summarizes the clinical manifestations and diagnosis and treatment scheme of SAPHO syndrome, and presents a case of patient with SAPHO syndrome who was treated in our department for bilateral tonsillectomy due to repeated pharyngalgia and fever for 10 years. Interestingly, the patient is getting better after the operation. The case is reported so as to provide reference for the diagnosis and treatment of SAPHO syndrome.
滑膜炎、痤疮、脓疱病、骨肥厚、骨炎综合征(SAPHO综合征)是一种累及骨骼、关节和皮肤的罕见疾病。由于其临床表现多样且普遍缺乏对该疾病的认识,它常常被误诊和误治。其发病机制尚未完全明确,因此,目前的治疗是经验性的,旨在控制炎症过程并减轻疼痛。本文总结了SAPHO综合征的临床表现、诊断和治疗方案,并介绍了1例在我科因反复咽痛、发热10年而行双侧扁桃体切除术的SAPHO综合征患者。有趣的是,该患者术后病情好转。报道此病例旨在为SAPHO综合征的诊断和治疗提供参考。