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组织活检和关节穿刺抽吸在人工髋关节周围感染诊断中的分析:横断面研究

ANALYSIS OF TISSUE BIOPSY AND JOINT ASPIRATION IN THE DIAGNOSIS OF PERIPROSTHETIC HIP INFECTIONS: CROSS-SECTIONAL STUDY.

作者信息

Andreolla Elton, Fernandes Marco Bernardo Cury, Lima Carla Ormundo Gonçalves Ximenes, Saraiva Augusto Carlos Maciel

机构信息

Instituto Nacional de Traumatologia e Ortopedia, Rio de Janeiro, RJ, Brazil.

出版信息

Acta Ortop Bras. 2021 Sep-Oct;29(5):242-245. doi: 10.1590/1413-785220212905241752.

Abstract

OBJECTIVE

To evaluate sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of preoperative joint aspiration (PJA) and periarticular tissue percutaneous biopsy (PTPB), as well as their combination, in the diagnosis of infection after total hip arthroplasty.

METHODS

This cross-sectional study (Level of Evidence II) was conducted with prospective data on 29 patients submitted to PJA with PTPB at the National Institute of Orthopedics and Traumatology from September 2015 to January 2016. Specimens obtained during the procedures underwent microbiological analyses, and the results were compared with those obtained in subsequent revision arthroplasty surgeries.

RESULTS

PJA, PTPB, and their combination reached values of 78%, 73%, 89% for sensitivity, respectively; 72%, 90%, 94% for specificity; and 76%, 80%, 90% for accuracy.

CONCLUSIONS

PJA combined with PTPB was sensitive, specific, and effective in diagnosing periprosthetic hip infection. .

摘要

目的

评估术前关节穿刺抽吸术(PJA)和关节周围组织经皮活检术(PTPB)及其联合应用在全髋关节置换术后感染诊断中的敏感性、特异性、准确性、阳性预测值和阴性预测值。

方法

这项横断面研究(证据等级II)采用了2015年9月至2016年1月在国家骨科与创伤研究所对29例行PJA和PTPB的患者的前瞻性数据。术中获取的标本进行了微生物分析,并将结果与随后的翻修关节置换手术中获得的结果进行比较。

结果

PJA、PTPB及其联合应用的敏感性分别达到78%、73%、89%;特异性分别为72%、90%、94%;准确性分别为76%、80%、90%。

结论

PJA联合PTPB在诊断人工髋关节周围感染方面具有敏感性、特异性且有效。

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Is there a role for tissue biopsy in the diagnosis of periprosthetic infection?组织活检在假体周围感染的诊断中有作用吗?
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本文引用的文献

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Prosthetic joint infection.人工关节感染
Clin Microbiol Rev. 2014 Apr;27(2):302-45. doi: 10.1128/CMR.00111-13.
7
Two-stage cementless revision of infected hip endoprostheses.感染性髋关节假体的两阶段非骨水泥翻修术。
Clin Orthop Relat Res. 2009 Jul;467(7):1848-58. doi: 10.1007/s11999-008-0611-y. Epub 2008 Nov 11.
8
Diagnosis of periprosthetic infection.人工关节周围感染的诊断
J Bone Joint Surg Am. 2006 Apr;88(4):869-82. doi: 10.2106/JBJS.E.01149.

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