社交接触对医护人员中 SARS-CoV-2 暴露的影响。

Impact of social contacts on SARS-CoV-2 exposure among healthcare workers.

机构信息

Department of Public Health, Faculty of Medicine, Dokuz Eylül University, Izmir 35340, Turkey.

Department of Occupational Medicine, Faculty of Medicine, Dokuz Eylül University, Izmir 35340, Turkey.

出版信息

Occup Med (Lond). 2022 Jan 13;72(1):10-16. doi: 10.1093/occmed/kqab141.

DOI:10.1093/occmed/kqab141

PMID:34633044

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8524522/

Abstract

BACKGROUND

Healthcare workers (HCWs) have an increased risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection due to occupational exposure. Strict measures generally focus on the patient-to-HCW contacts. However, interactions between the HCWs also pose a high risk for SARS-CoV-2 exposure.

AIMS

This study was aimed to investigate the effect of social contacts on the level of SARS-CoV-2 exposure risk among workers by broadening the current risk assessment algorithm.

METHODS

Contact tracing records of the workers in a large university hospital between 19th March and 31st December 2020 were analysed. Multivariate conditional logistic regression models were estimated to evaluate factors associated with high-risk exposure for contacts among workers.

RESULTS

Of the 329 exposed clusters, 260 (79%) were HCW-to-HCW contacted clusters. High-risk exposure was higher in the HCW-to-HCW contacts (44%), when compared to the patient-to-HCW contacts (5%) (P < 0.001). A total of 1827 HCWs contacted a laboratory-confirmed COVID-19-positive co-worker. Among the HCW-to-HCW contacts, high-risk exposure was higher in the support staff (49%, P < 0.001), in non-patient care settings (47%, P < 0.001) and in the social contacts (57%, P < 0.001). Social contacts between workers increased the high-risk exposure (adjusted odds ratio: 3.50, 95% confidence interval 2.62-4.69) in multivariate analysis.

CONCLUSIONS

A significant association between social contacts among workers and high-risk exposure of SARS-CoV-2 was observed. The results of the study emphasize the need for policies regarding the improved protection of HCWs in social settings in addition to patient care services.

摘要

背景

由于职业接触，医护人员（HCWs）感染严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）的风险增加。一般来说，严格的措施主要集中在患者与 HCW 的接触上。然而，HCW 之间的相互作用也会使 SARS-CoV-2 暴露的风险很高。

目的

本研究旨在通过拓宽当前的风险评估算法，研究社会接触对工人中 SARS-CoV-2 暴露风险水平的影响。

方法

分析了 2020 年 3 月 19 日至 12 月 31 日期间一家大型大学医院工作人员的接触追踪记录。使用多变量条件逻辑回归模型评估工人中与接触相关的高风险暴露因素。

结果

在 329 个暴露群中，有 260 个（79%）是 HCW 之间的接触群。与患者与 HCW 的接触（5%）相比，HCW 之间的高风险暴露（44%）更高（P < 0.001）。共有 1827 名 HCW 接触过实验室确诊的 COVID-19 阳性同事。在 HCW 之间的接触中，支持人员（49%，P < 0.001）、非患者护理环境（47%，P < 0.001）和社交接触（57%，P < 0.001）的高风险暴露更高。在多变量分析中，工人之间的社交接触增加了高风险暴露（调整后的优势比：3.50，95%置信区间 2.62-4.69）。