Division of Pulmonary and Critical Care, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Department of Pulmonary and Critical Care, Northeast Georgia Health System, Gainesville, Georgia, USA.
J Med Virol. 2022 Mar;94(3):945-950. doi: 10.1002/jmv.27384. Epub 2021 Oct 26.
Disparities in outcomes exist in outcomes of coronavirus disease-19 (COVID-19). Little is known about other ethnic minorities in United States. We included all COVID-19 positive adult patients (≥18 years) hospitalized between March 1, 2020 and February 5th 2021. We compared in hospital mortality, use of intensive care unit services and inflammatory markers between non-Hispanic whites with non-White/Black Hispanic. Multivariable Cox proportional Hazard models were used to adjust for differences between the two groups. There were 4059 hospital admissions with COVID-19 in the study period. Of the 3288 White, 789 (24%) required intensive care unit (ICU) admission in comparison to 187 (24.3%) of the 770 Hispanics. Unadjusted mortality was higher in Whites than Hispanics (17.1% vs. 10.7%; p < 0.001). After adjusting for confounding variables, in-hospital mortality was not statistically different for Whites in comparison to Hispanics (hazard ratio [HR]: 0.96, 95% confidence interval [CI]: 0.76-1.21, p = 0.73). The adjusted rates of ICU transfers were significantly higher in Hispanics (HR: 1.34, 95% CI: 1.11-1.61, p = 0.002). Hispanics had significantly higher C-reactive protein, lactate dehydrogenase, and fibrinogen when compared to Whites. Hispanics as compared to Whites with COVID-19 require higher rates of ICU admission but have a similar mortality. Hispanics as compared to Whites with COVID-19 require higher rates of ICU admission but have a similar mortality.
在冠状病毒病-19（COVID-19）的结果中存在差异。对于美国的其他少数族裔知之甚少。我们纳入了所有 2020 年 3 月 1 日至 2021 年 2 月 5 日期间住院的 COVID-19 阳性成年患者（≥18 岁）。我们比较了非西班牙裔白人与非白/黑西班牙裔之间的住院死亡率、重症监护病房服务使用情况和炎症标志物。多变量 Cox 比例风险模型用于调整两组之间的差异。在研究期间，有 4059 例 COVID-19 住院患者。在 3288 名白人中，有 789 人（24%）需要入住重症监护病房（ICU），而在 770 名西班牙裔中，有 187 人（24.3%）需要入住 ICU。未经调整的死亡率在白人中高于西班牙裔（17.1%比 10.7%；p<0.001）。在校正混杂因素后，白人的住院死亡率与西班牙裔无统计学差异（风险比[HR]：0.96，95%置信区间[CI]：0.76-1.21，p=0.73）。西班牙裔 ICU 转率明显高于白人（HR：1.34，95% CI：1.11-1.61，p=0.002）。与白人相比，西班牙裔的 C 反应蛋白、乳酸脱氢酶和纤维蛋白原水平明显更高。与白人 COVID-19 患者相比，西班牙裔患者需要更高的 ICU 入住率，但死亡率相似。
