Department of Family Medicine, Department of Psychology, Loma Linda University, USA.
School of Public Health, Loma Linda University, USA.
J Psychosom Res. 2021 Dec;151:110633. doi: 10.1016/j.jpsychores.2021.110633. Epub 2021 Sep 28.
Adverse Childhood Experiences (ACEs) consistently predict poor mental and physical health as well as early all-cause mortality. Much work examines health harming behaviors that may be used to cope with ACEs associated stress responses and dysregulation. Limited research has been conducted assessing plant-based dietary intake on the ACEs and mortality relationship. We investigate moderators of the ACEs and mortality association including plant-based dietary intake.
The purpose of this study is to examine if the association between ACEs and early mortality is potentially moderated by plant-based dietary intake.
An observational, prospective cohort study that included 9301 Seventh-day Adventists were assessed from 2006 to 2017 in the Biopsychosocial Religion and Health Study (BRHS).
We examined the potential impact of plant-based intake frequency on the ACEs and all-cause mortality relationship, while adjusting for potential confounders (e.g., demographics, health risks, mental and physical health) in a cox regression survival analysis.
ACEs were adversely associated with survival time (HR = 2.76, 95% CI: 1.15-6.64). Plant-based intake was associated with a reduction in the association of 4+ ACEs with early mortality (HR = 0.73, 95% CI: 0.59-0.90) above and beyond demographics, animal-based intake, physical health, mental health, BMI, exercise, and worship. We estimate that after 4+ ACEs, those eating high versus low plant-based dietary intake may live 5.4 years longer.
Plant-based dietary intake may potentially moderate the ACEs and early mortality relationship; however, observational studies cannot determine causality.
不良童年经历（ACEs）一直预测着较差的身心健康和早逝。许多研究都在关注可能用于应对与 ACEs 相关的应激反应和失调的有害健康行为。关于植物性饮食摄入对 ACEs 和死亡率关系的研究有限。我们调查了 ACEs 和死亡率关系的调节因素，包括植物性饮食摄入。
本研究旨在检验 ACEs 和早逝之间的关联是否可能受到植物性饮食摄入的调节。
本研究是一项观察性、前瞻性队列研究，2006 年至 2017 年期间，共有 9301 名基督复临安息日会教徒参与了生物心理社会宗教与健康研究（BRHS）。
我们通过 Cox 回归生存分析，检验了植物性饮食摄入频率对 ACEs 和全因死亡率关系的潜在影响，同时调整了潜在的混杂因素（例如，人口统计学、健康风险、身心健康）。
ACEs 与生存时间呈负相关（HR=2.76，95%CI：1.15-6.64）。植物性饮食摄入与 ACEs 与早逝之间的关联呈负相关（HR=0.73，95%CI：0.59-0.90），这一关联超出了人口统计学、动物源性饮食摄入、身体健康、心理健康、BMI、运动和礼拜等因素。我们估计，在经历了 4 次以上 ACEs 后，那些高植物性饮食摄入的人与低植物性饮食摄入的人相比，可能会多活 5.4 年。
植物性饮食摄入可能会调节 ACEs 和早逝之间的关系；然而，观察性研究无法确定因果关系。
