Tianjin Key Laboratory of Environmental Technology for Complex Trans-Media Pollution and Tianjin International Joint Research Center for Environmental Biogeochemical Technology, College of Environmental Science and Engineering, Nankai University, Tianjin, 300350, China.
Department of Soils and Agri-Food Engineering, Paul Comtois Bldg., Laval University, Quebec City, QC, G1K 7P4, Canada.
Talanta. 2022 Jan 1;236:122875. doi: 10.1016/j.talanta.2021.122875. Epub 2021 Sep 11.
Molecularly imprinted polymers (MIPs) have aroused great attention as a new material for the removal or detection of pharmaceuticals and personal care products (PPCPs). However, it is not clear about the superiority and deficiency of MIPs in the process of removing or detecting PPCPs. Herein, we evaluated the performance of MIPs in the aspects of adsorption capacity, binding affinity, adsorption rate, and compatibility to other techniques, and proposed ways to improve its performance. Without regard to the selectivity of MIPs, for the PPCPs adsorption, MIPs surprisingly did not always perform better than the conventional adsorbents (non-imprinted polymers, biochar, activated carbon and resin), indicating that MIPs should be used where selectivity is crucial, for example recovery of specific PPCPs in an environmental sample extraction process. Compared to the traditional solid-phase extraction for PPCPs detection pretreatment, the usage of MIPs as substitute extraction agents could obtain high selectivity of specific substance, due to the uniformity and effectiveness of the specific sites. A promising development in the future would be to combine other simple and rapid quantitative technologies, such as electro/photochemical sensor and catalytic degradation, to realize rapid and sensitive detection of trace PPCPs.
分子印迹聚合物（MIPs）作为一种新型材料，在去除或检测药品和个人护理产品（PPCPs）方面引起了极大的关注。然而，MIPs 在去除或检测 PPCPs 过程中的优势和不足尚不清楚。在此，我们从吸附容量、结合亲和力、吸附速率以及与其他技术的兼容性等方面评估了 MIPs 的性能，并提出了改进其性能的方法。不考虑 MIPs 的选择性，对于 PPCPs 的吸附，MIPs 并不总是比传统吸附剂（非印迹聚合物、生物炭、活性炭和树脂）表现更好，这表明 MIPs 应在选择性至关重要的地方使用，例如在环境样品提取过程中回收特定的 PPCPs。与传统的用于 PPCPs 检测预处理的固相萃取相比，MIPs 作为替代萃取剂的使用可以获得特定物质的高选择性，这是由于特定位点的均匀性和有效性。未来一个有前途的发展方向是将其他简单快速的定量技术，如电化学/光化学传感器和催化降解，结合起来，实现对痕量 PPCPs 的快速灵敏检测。
