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2016 年至 2017 年韩国分离株的血清型分布和抗菌药物耐药性。

Serotype Distribution and Antimicrobial Resistance of Isolates in Korea between 2016 and 2017.

机构信息

Department of Clinical Laboratory Science, Semyung University, Jecheon, Korea.

Busan Institute of Health and Environment, Busan, Korea.

出版信息

Ann Lab Med. 2022 Mar 1;42(2):268-273. doi: 10.3343/alm.2022.42.2.268.

Abstract

is one of the major causes of food-borne infections. We investigated the serotype distribution and antimicrobial resistance of isolates collected in Korea between January 2016 and December 2017. In total, 669 isolates were collected from clinical specimens at 19 university hospitals. Serotyping was performed according to the Kauffmann-White scheme, and antimicrobial susceptibility was tested using Sensititre EUVSEC plates or disk diffusion. Among the strains, C (39.8%) and B (36.6%) were the most prevalent serogroups. In total, 51 serotypes were identified, and common serotypes were . enterica serovar I 4,[5],12:i:- (16.7%), . Enteritidis (16.1%), . Bareilly (14.6%), . Typhimurium (9.9%), and . Infantis (6.9%). The resistance rates to ampicillin, chloramphenicol, and trimethoprim-sulfamethoxazole were 32.6%, 12.1%, and 8.4%, respectively. The resistance rates to cefotaxime and ciprofloxacin were 8.1% and 3.0%, respectively, while 5.4% were multidrug-resistant. serovar I 4,[5],12:i:- and . Enteritidis were highly prevalent, and there was an increase in rare serotypes. Multidrug resistance and ciprofloxacin resistance were highly prevalent. Periodic investigations of serotypes and antimicrobial resistance are needed.

摘要

是食源性感染的主要原因之一。我们调查了 2016 年 1 月至 2017 年 12 月期间在韩国收集的分离株的血清型分布和抗菌药物耐药性。共从 19 所大学医院的临床标本中收集了 669 株分离株。血清分型按照 Kauffmann-White 方案进行,抗菌药物敏感性试验采用 Sensititre EUVSEC 平板或纸片扩散法进行。在这些菌株中,C(39.8%)和 B(36.6%)是最常见的血清群。共鉴定了 51 种血清型,常见的血清型为. enterica 血清型 I 4,[5],12:i:-(16.7%)、. Enteritidis(16.1%)、. Bareilly(14.6%)、. Typhimurium(9.9%)和. Infantis(6.9%)。氨苄西林、氯霉素和甲氧苄啶-磺胺甲恶唑的耐药率分别为 32.6%、12.1%和 8.4%。头孢噻肟和环丙沙星的耐药率分别为 8.1%和 3.0%,而 5.4%为多药耐药。. Enteritidis 血清型 I 4,[5],12:i:-和. Enteritidis 血清型高度流行,罕见血清型有所增加。多药耐药和环丙沙星耐药率较高。需要定期调查 血清型和抗菌药物耐药性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/527b/8548255/3abc221c9ae3/alm-42-2-268-f1.jpg

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