Santarelli Shana, Morgan Madison E, Vernon Tawnya, Bradburn Eric, Perea Lindsey L
6556Philadelphia College of Osteopathic Medicine, Philadelphia, PA, USA.
Research Institute, 209639Penn Medicine Lancaster General Health, Lancaster, PA, USA.
Am Surg. 2022 May;88(5):866-872. doi: 10.1177/00031348211048842. Epub 2021 Oct 13.
Unplanned readmission/bounceback to the intensive care unit (ICUBB) is a prevalent issue in the medical community. The geriatric population is incompletely studied in regard to ICUBB. We sought to determine if ICUBB in older patients was associated with higher risk of mortality. We hypothesized that, of those who were older, those with ICUBB would have higher mortality compared to those with no ICUBB. Further, we hypothesized that of those with ICUBB, older age would lead to higher mortality.
The Pennsylvania Trauma Outcome Study database was retrospectively queried from 2003 to 2018 for all trauma patients of age ≥40 years. Those with advance directives were excluded. Adjusted analysis in the form of logistic regressions controlling for demographic and injury covariates and clustering by facility were used to assess the adjusted impact of ICUBB and age on mortality.
363,778 patients were aged ≥40 years. When comparing mortalities between the age 40 and 49 years group and those in older groups, a dramatic increase in mortality was observed between those in each respective age category with ICUBB vs non-ICUBB. This trend was most prominent in those in the 90+ years age group (ICUBB: AOR: 34.78, < .001; non-ICUBB: AOR: 9.08, < .001). A second model only including patients who had ICUBB found that patients of age ≥65 years had significantly higher odds of mortality (AOR: 4.10, < .001) when compared to their younger counterparts (age <65 years).
An ICUBB seems to exacerbate mortality rates as age increases. This profound increase in mortality calls for strategies to be developed, especially in the older population, to attempt to mitigate the factors leading to ICUBB.
非计划重返重症监护病房(ICUBB)是医学界普遍存在的问题。老年人群体在ICUBB方面的研究尚不充分。我们试图确定老年患者的ICUBB是否与更高的死亡风险相关。我们假设,在老年患者中,发生ICUBB的患者比未发生ICUBB的患者死亡率更高。此外,我们假设在发生ICUBB的患者中,年龄越大,死亡率越高。
对宾夕法尼亚创伤结局研究数据库进行回顾性查询,纳入2003年至2018年所有年龄≥40岁的创伤患者。排除有预先指示的患者。采用逻辑回归形式的校正分析,控制人口统计学和损伤协变量,并按医疗机构进行聚类,以评估ICUBB和年龄对死亡率的校正影响。
363,778名患者年龄≥40岁。在比较40至49岁年龄组与老年组的死亡率时,发现各年龄类别中发生ICUBB与未发生ICUBB的患者之间死亡率急剧上升。这种趋势在90岁以上年龄组中最为明显(ICUBB:调整后比值比[AOR]:34.78,P<0.001;非ICUBB:AOR:9.08,P<0.001)。第二个模型仅纳入发生ICUBB的患者,发现年龄≥65岁的患者与年轻患者(年龄<65岁)相比,死亡几率显著更高(AOR:4.10,P<0.001)。
随着年龄增长,ICUBB似乎会加剧死亡率。死亡率的大幅上升需要制定策略,尤其是针对老年人群体,以试图减轻导致ICUBB的因素。