Jwa Seung Chik, Ishihara Osamu, Kuwahara Akira, Saito Kazuki, Saito Hidekazu, Terada Yukihiro, Kobayashi Yasuki, Maeda Eri
Department of Obstetrics and Gynecology Saitama Medical University Saitama Japan.
Department of Obstetrics and Gynecology Graduate School of Biomedical Sciences Tokushima University Tokushima Japan.
Reprod Med Biol. 2021 Jun 20;20(4):451-459. doi: 10.1002/rmb2.12397. eCollection 2021 Oct.
We investigated the cumulative live birth rate (CLBR) in women receiving governmental subsidies for assisted reproductive technology (ART) in Saitama Prefecture, Japan.
Women who applied for subsidies from Saitama Prefectural Government for the first time in 2016 were enrolled and followed up until the end of 2017. Treatment information, including live birth, was obtained from the Japanese ART registry by linking it with unique identification numbers for treatment. Patients' factors associated with having a live birth were investigated.
Of 1,072 women (2,513 applications), 495 (46.2%) had a live birth with 8 (1.6%) twin pregnancies. The CLBR over six subsidized cycles was 53.7% for women aged <40 years, and 17.2% over three subsidized cycles for women 40-42 years; highest among women <35 years (58.4%), followed by those aged 35-39 years (49.3%). Multivariate analysis revealed patient age as the only independent factor for having a live birth.
The CLBR of women receiving subsidies for ART was greatest in women aged <35 years. Effective policies for promoting ART among younger couples who seek infertility treatment are essential.
我们调查了在日本埼玉县接受政府辅助生殖技术(ART)补贴的女性的累积活产率(CLBR)。
纳入2016年首次向埼玉县政府申请补贴的女性,并随访至2017年底。通过将治疗信息与治疗的唯一识别码相关联,从日本ART登记处获取包括活产在内的治疗信息。调查与活产相关的患者因素。
在1072名女性(2513次申请)中,495名(46.2%)活产,其中8名(1.6%)为双胎妊娠。年龄<40岁的女性在六个补贴周期内的CLBR为53.7%,40 - 42岁的女性在三个补贴周期内的CLBR为17.2%;<35岁的女性中CLBR最高(58.4%),其次是35 - 39岁的女性(49.3%)。多因素分析显示患者年龄是活产的唯一独立因素。
接受ART补贴的女性中,<35岁的女性CLBR最高。针对寻求不孕治疗的年轻夫妇制定有效的ART推广政策至关重要。