Ishihara Osamu, Jwa Seung Chik, Kuwahara Akira, Katagiri Yukiko, Kuwabara Yoshimitsu, Hamatani Toshio, Harada Miyuki, Osuga Yutaka
Department of Obstetrics and Gynecology Saitama Medical University Saitama Japan.
Department of Obstetrics and Gynecology Graduate School of Biomedical Sciences Tokushima University Tokushima Japan.
Reprod Med Biol. 2020 Nov 20;20(1):3-12. doi: 10.1002/rmb2.12358. eCollection 2021 Jan.
Since 2007, the Japan Society of Obstetrics and Gynecology (JSOG) has collected cycle-based data for assisted reproductive technology (ART) in an online registry. Here, we present the characteristics and treatment outcomes of ART cycles registered during 2018.
The Japanese ART registry consists of cycle-specific information for all ART treatment cycles implemented at 621 participating facilities. We conducted descriptive analyses for such cycles registered for 2018.
In total, 454 893 treatment cycles and 56 979 neonates were reported in 2018: both increased from 2017. The mean maternal age was 38.0 years (standard deviation ± 4.7). Of 247 402 oocyte retrievals, 118 378 (47.8%) involved freeze-all-embryos cycles; fresh embryo transfer (ET) was performed in 50 463 cycles: a decreasing trend since 2015. A total of 199 914 frozen-thawed ET cycles were reported, resulting in 69 357 pregnancies and 49 360 neonates born. Single ET (SET) was performed in 82.2% of fresh transfers and 83.4% of frozen-thawed cycles, with singleton pregnancy/live birth rates of 97.2%/97.2% and 97.0%/97.2%, respectively.
Total ART cycles and subsequent live births increased in 2018. SET was performed in over 80% of cases, and the mode of ET has shifted continuously from using fresh embryos to frozen-thawed ones compared with previous years.
自2007年以来，日本妇产科学会（JSOG）已通过在线登记系统收集辅助生殖技术（ART）基于周期的数据。在此，我们呈现2018年登记的ART周期的特征和治疗结果。
日本ART登记系统包含在621家参与机构实施的所有ART治疗周期的特定周期信息。我们对2018年登记的此类周期进行了描述性分析。
2018年共报告了454893个治疗周期和56979例新生儿：两者均较2017年有所增加。产妇平均年龄为38.0岁（标准差±4.7）。在247402次取卵中，118378次（47.8%）涉及全胚冷冻周期；50463个周期进行了新鲜胚胎移植（ET）：自2015年以来呈下降趋势。共报告了199914个冻融ET周期，产生69357例妊娠和49360例新生儿出生。82.2% 的新鲜移植和83.4% 的冻融周期进行了单胚胎移植（SET），单胎妊娠/活产率分别为97.2%/97.2% 和97.0%/97.2%。
2018年ART总周期数和随后的活产数有所增加。超过80% 的病例进行了SET，与前几年相比，ET方式已持续从使用新鲜胚胎转向冻融胚胎。
