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杨梅素:对其生物学潜力的全面综述

Myricetin: A comprehensive review on its biological potentials.

作者信息

Imran Muhammad, Saeed Farhan, Hussain Ghulam, Imran Ali, Mehmood Zaffar, Gondal Tanweer Aslam, El-Ghorab Ahmed, Ahmad Ishtiaque, Pezzani Raffaele, Arshad Muhammad Umair, Bacha Umar, Shariarti Mohammad Ali, Rauf Abdur, Muhammad Naveed, Shah Zafar Ali, Zengin Gokhan, Islam Saiful

机构信息

Faculty of Allied Health Sciences University Institute of Diet and Nutritional Sciences The University of Lahore Lahore Pakistan.

Department of Food Science Institute of Home and Food Sciences Government College University Faisalabad Pakistan.

出版信息

Food Sci Nutr. 2021 Aug 11;9(10):5854-5868. doi: 10.1002/fsn3.2513. eCollection 2021 Oct.

Abstract

Myricetin is a critical nutritive component of diet providing immunological protection and beneficial for maintaining good health. It is found in fruits, vegetables, tea, and wine. The families , , , and are the richest sources of myricetin. Different researchers explored the therapeutic potential of this valuable constituent such as anticancer, antidiabetic, antiobesity, cardiovascular protection, osteoporosis protection, anti-inflammatory, and hepatoprotective. In addition to these, the compound has been tested for cancer and diabetic mellitus during clinical trials. Health benefits of myricetin are related to its impact on different cell processes, such as apoptosis, glycolysis, cell cycle, energy balance, lipid level, serum protein concentrations, and osteoclastogenesis. This review explored the potential health benefits of myricetin with a specific emphasis on its mechanism of action, considering the most updated and novel findings in the field.

摘要

杨梅素是饮食中的一种关键营养成分,具有免疫保护作用,有助于保持身体健康。它存在于水果、蔬菜、茶和葡萄酒中。[此处原文中“families”后接的逗号和四个逗号及空格处似乎信息不完整,无法准确翻译这部分内容]是杨梅素最丰富的来源。不同的研究人员探索了这种有价值成分的治疗潜力,如抗癌、抗糖尿病、抗肥胖、心血管保护、骨质疏松保护、抗炎和肝脏保护作用。除此之外,该化合物已在临床试验中针对癌症和糖尿病进行了测试。杨梅素对健康的益处与其对不同细胞过程的影响有关,如细胞凋亡、糖酵解、细胞周期、能量平衡、血脂水平、血清蛋白浓度和破骨细胞生成。本综述探讨了杨梅素潜在的健康益处,并特别强调了其作用机制,同时考虑了该领域最新和新颖的研究发现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8e9/8498061/fd3a812becc8/FSN3-9-5854-g003.jpg

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