Teerakanok Jirapat, DeWitt Judy Park, Juarez Edna, Thein Kyaw Zin, Warraich Irfan
Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79430, United States.
School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79430, United States.
World J Gastrointest Oncol. 2017 Oct 15;9(10):431-435. doi: 10.4251/wjgo.v9.i10.431.
Primary non-Hodgkin lymphomas in the esophagus are rare. Tracheoesophageal fistulas mainly arise from solid esophageal carcinoma or mediastinal malignancies. Our patient presented with cough, dysphagia and weight loss, and upon initial computed tomography imaging and esophagogastroduodenoscopy, a malignant mass in the middle third of esophagus with tracheoesophageal fistula was found. The location of the mass and presence of malignant tracheoesophageal fistula were strongly suggestive of squamous cell carcinoma. However, tumor biopsy revealed diffuse large B-cell lymphoma. This case report details a rare incident of a primary diffuse large B-cell lymphoma presented as tracheoesophageal fistula and reviews previous literature.
原发性食管非霍奇金淋巴瘤很罕见。气管食管瘘主要由食管实体癌或纵隔恶性肿瘤引起。我们的患者表现为咳嗽、吞咽困难和体重减轻，经初次计算机断层扫描成像和食管胃十二指肠镜检查，发现食管中段有一恶性肿块并伴有气管食管瘘。肿块的位置及恶性气管食管瘘的存在强烈提示为鳞状细胞癌。然而，肿瘤活检显示为弥漫性大B细胞淋巴瘤。本病例报告详细介绍了一例表现为气管食管瘘的原发性弥漫性大B细胞淋巴瘤的罕见病例，并回顾了既往文献。
