Haddad Sasha, Uebelhoer Nathan S, Erickson Christof, Calame Antoanella, Cohen Philip R
Dermatology, A.T. Still University, School of Osteopathic Medicine, Mesa, USA.
Dermatologic Surgery, San Diego Family Dermatology, National City, USA.
Cureus. 2021 Sep 3;13(9):e17695. doi: 10.7759/cureus.17695. eCollection 2021 Sep.
A dystrophic nail is an alteration of the physical appearance and structural properties of the nail from its shape, color, and texture, which can result from multiple etiologies. Calcinosis cutis is a condition that refers to the calcium deposition in the skin and underlying tissue. A 55-year-old man who presented with a split right thumbnail associated with subungual calcinosis cutis affecting the same digit for a duration of nine years is described. He did not recall trauma to the affected area. Microscopic evaluation of the tissue specimen obtained following a biopsy of the affected digit's nail matrix showed foci of calcium in the dermis. The correlation of his clinical presentation and biopsy findings established a diagnosis of subungual calcinosis cutis. Subungual calcification has been observed in several clinical settings. In addition to subungual calcinosis cutis, it has been noted as a normal finding in elderly individuals. In addition, it has been observed in patients with scleroderma or following trauma to the site. Less commonly, subungual calcification can be associated with idiopathic conditions: calcifying aponeurotic fibroma, digital calcinosis circumscripta, subepidermal calcified nodule, and calcified subungual epidermoid inclusion.
营养不良性指甲是指甲的外观和结构特性在形状、颜色和质地方面发生的改变，其可由多种病因引起。皮肤钙化症是指钙在皮肤及皮下组织中的沉积。本文描述了一名55岁男性，其右拇指指甲裂开并伴有甲下皮肤钙化症，累及同一手指长达九年。他不记得患部受过外伤。对患指指甲基质活检后获得的组织标本进行显微镜评估，结果显示真皮中有钙沉积灶。其临床表现与活检结果相互印证，确诊为甲下皮肤钙化症。甲下钙化在多种临床情况下均有观察到。除甲下皮肤钙化症外，在老年人中它被视为正常表现。此外，在硬皮病患者或患部受过外伤的患者中也观察到了甲下钙化。较少见的情况下，甲下钙化可与特发性疾病相关：钙化性腱膜纤维瘤、局限性指端钙化症、表皮下钙化结节和钙化性甲下表皮样包涵体。
