Since the outbreak of COVID-19, there has been a surge of discrimination against Asians across the globe. However, there is a knowledge gap of COVID-19 related racial discrimination against Asians in smaller Asian populations. A total of 221 adults living in Florida completed an online survey between June-July 2020. Adjusted logistic regression assessed associations between sociodemographic factors and experienced discrimination, hypervigilance of safety, nervousness in public, and anticipated discrimination. Statistical analyses were performed using SPSS. Asian respondents were more likely than non-Asians to experience discrimination during COVID-19 (AOR = 12.58; 95% CI 4.74, 33.38; p ≤ 0.001). Asians were more likely to anticipate discrimination after the pandemic ends (AOR = 4.35, 95% CI 1.33, 14.17; p < 0.05). We found that Asians in smaller Asian populations suffer from a disproportionate level of discrimination due to COVID-19, relative to non-Asians. Our findings support previous research that racial discrimination exists on a continuum of violence and can have severe negative health consequences.