University Hospital of Dermatology and Venereology, Damascus University, Damascus, Syria.
J Med Case Rep. 2021 Oct 17;15(1):512. doi: 10.1186/s13256-021-03124-6.
Basal cell carcinoma is the most common nonmelanotic skin cancer. It has variable clinical and histological subtypes that vary in their aggressiveness and liability to recurrence and metastasis. Chronic ultraviolet radiation exposure is considered to be the main risk factor for developing basal cell carcinoma; therefore, it typically arises on sun-exposed skin, mainly the head and neck.
We present the case of a 55-year-old Caucasian male who presented with a lesion on the scrotum for 2 years. The lesion was clinically presumed benign and initially treated with curettage. Microscopic examination revealed an incompletely resected micronodular basal cell carcinoma with sebaceous differentiation. Therefore, a second excisional biopsy was performed to completely excise the incidentally discovered malignant tumor.
We report the first case of micronodular basal cell carcinoma arising on the scrotum. The goal of our article is to draw clinicians' attention to the possible involvement of unexposed skin with basal cell carcinoma, and we highlight the importance of accurate diagnosis and prompt treatment due to the aggressive nature of micronodular basal cell carcinoma.
基底细胞癌是最常见的非黑色素皮肤癌。它具有不同的临床和组织学亚型,在侵袭性、复发和转移的倾向方面存在差异。慢性紫外线辐射暴露被认为是发展基底细胞癌的主要危险因素;因此,它通常发生在暴露于阳光的皮肤,主要是头部和颈部。
我们报告了一例 55 岁白人男性,阴囊上有一个病变 2 年。病变最初被临床诊断为良性,并进行了刮除术。显微镜检查显示不完全切除的微结节状基底细胞癌伴皮脂腺分化。因此,进行了第二次切除活检以完全切除偶然发现的恶性肿瘤。
我们报告了首例阴囊微结节状基底细胞癌。我们的目的是引起临床医生对基底细胞癌可能累及未暴露皮肤的关注,并强调由于微结节状基底细胞癌的侵袭性,准确诊断和及时治疗的重要性。