Acıbadem Mehmet Ali Aydınlar University, School of Medicine, Department of Neurosurgery, Istanbul, Turkey.
Bahçeşehir University, School of Medicine, Department of Physical Medicine and Rehabilitation, Istanbul, Turkey.
J Clin Neurosci. 2021 Nov;93:147-154. doi: 10.1016/j.jocn.2021.09.023. Epub 2021 Sep 20.
There are case reports and small case series in the literature reporting gas-filled pseudocysts (GFP). However, a systematic review presenting overall view of the disease and its management is still lacking. In the present study, we aimed to make a systematic review of GFP cases, and present an exemplary case of ours. Our second aim was to discuss current theories for pathogenesis of GFP. A systematic review of GFP was conducted using Preferred Reporting Items for Systematic Reviews and Meta-Analyses guideline. Two large-scaled data search engines were used. A total of 53 articles were retrieved from the literature and presented with an exemplary case of ours. Mean age of the historical cohort was 59.47 years. There were 66 male (54.1%) and 56 female (45.9%) patients. The most prevalent clinical presentation was radicular sign/symptom in lower limbs with (29.1%) or without low back pain (LBP) (67%). Gas-filled pseudocyst has most commonly been diagnosed at the lower lumbar spine (L4-L5, 45.3%; L5-S1, 37.7%). Surgery was the treatment of choice in most of the patients (80%). In the whole cohort, 79.1% of the patients had complete recovery. Gas-filled pseudocysts are rarely observed in daily practice. They present mostly in men at the age of 60s. Precise differential diagnosis determination using appropriate imaging would help clinicians treat the patients properly. Gas-filled pseudocysts should be treated similarly to other spinal pathologies causing nerve root compression.
文献中有关于气囊肿性假性囊肿 (GFP) 的病例报告和小病例系列。然而，仍然缺乏对该疾病及其治疗的全面系统评价。在本研究中，我们旨在对 GFP 病例进行系统评价，并展示我们的一个示例病例。我们的第二个目的是讨论 GFP 发病机制的当前理论。使用系统评价和荟萃分析的首选报告项目 (PRISMA) 指南对 GFP 进行了系统评价。使用了两个大型数据搜索引擎。从文献中检索到 53 篇文章，并展示了我们的一个示例病例。历史队列的平均年龄为 59.47 岁。有 66 名男性 (54.1%) 和 56 名女性 (45.9%) 患者。最常见的临床表现是下肢神经根症状/体征，伴有 (29.1%) 或不伴有腰痛 (LBP) (67%)。气囊肿性假性囊肿最常被诊断为下腰椎 (L4-L5，45.3%；L5-S1，37.7%)。大多数患者 (80%) 首选手术治疗。在整个队列中，79.1%的患者完全康复。气囊肿性假性囊肿在日常实践中很少见。它们主要发生在 60 多岁的男性中。使用适当的影像学进行精确的鉴别诊断有助于临床医生正确治疗患者。气囊肿性假性囊肿的治疗应类似于其他引起神经根受压的脊柱病变。
