Erdem Nazan Şimşek, Özkaynak Sehur Sibel
Akdeniz University, Department of Neurology, Antalya, Turkey.
Ideggyogy Sz. 2021 Sep 30;74(9-10):356-360. doi: 10.18071/isz.74.0356.
Pisa syndrome is a movement problem defined by tonic, sustained lateral flexion with a slight posterior rotation of the trunk. It seems to be a side effect of antipsychotic medicine in most cases. The clinical duration of Pisa syndrome can be acute, chronic, or recurrent. As far as we know, no reports are available in the literature on the chronic form of Pisa syndrome caused by low-dose amisulpride. A case of refractory tardive dystonia form of Pisa syndrome during treatment with stable low-dose amisulpride is presented in this report. Long-term, low-dosage amisulpride therapy may induce tardive dystonia even in patients with no other risk factors for dystonia.
Pisa综合征是一种运动障碍，其特征为强直性、持续性的身体侧屈，并伴有躯干轻度后旋。在大多数情况下，它似乎是抗精神病药物的副作用。Pisa综合征的临床病程可以是急性、慢性或复发性的。据我们所知，文献中尚无关于低剂量氨磺必利引起慢性Pisa综合征的报道。本报告介绍了1例在稳定低剂量氨磺必利治疗期间出现难治性迟发性肌张力障碍型Pisa综合征的病例。即使在没有其他肌张力障碍危险因素的患者中，长期低剂量氨磺必利治疗也可能诱发迟发性肌张力障碍。
