Wojas Oksana, Arcimowicz Magdalena, Furmańczyk Konrad, Sybilski Adam, Raciborski Filip, Tomaszewska Aneta, Walkiewicz Artur, Samel-Kowalik Piotr, Samoliński Bolesław, Krzych-Fałta Edyta
Department of Prevention of Environmental Hazards and Allergology, Faculty of Health Sciences, Medical University of Warsaw, Warsaw, Poland.
Department of Otorhinolaryngology Head and Neck Surgery, Medical University of Warsaw, Warsaw, Poland.
Postepy Dermatol Alergol. 2021 Aug;38(4):650-656. doi: 10.5114/ada.2020.94400. Epub 2021 May 4.
Nasal polyps are frequently associated with bronchial asthma and rhinitis. The chronic nature of the symptoms, the high post-treatment recurrence rates, as well as various comorbidities, constitute key factors that significantly affect the quality of life of patients diagnosed with this condition.
The purpose of the study was to estimate the prevalence of nasal polyps in the examined population and to assess the possible associative occurrence of nasal polyps (NP) with bronchial asthma (BA), allergic (AR) and non-allergic rhinitis (NAR), and atopic dermatitis (AD).
The ECRHS II and ISAAC questionnaires of the study group of 18,458 individuals, including 4,473 6-7-year-olds (24.2%), 4,675 13-14-year-olds (25.4%), and 9,310 20-44-year-olds (50.4%) were performed.
The prevalence of nasal polyps in the examined group was 1.1%, reported by a total of 204 individuals. Nasal polyps were reported more frequently among urban residents (191 (1.1%)) than rural residents (13 (0.6%)). Our study demonstrated a correlation between the presence of nasal polyps and asthma, as well as allergic and non-allergic rhinitis The greatest risk factor for NP in the evaluated subpopulation with multiple allergic conditions was the co-existence of non-allergic rhinitis and atopic dermatitis (OR = 6.09; 95% CI: 3.4-10.93).
Nasal polyps are relatively rare in the evaluated Polish population. Nonetheless, we believe their co-occurrence with non-allergic rhinitis, allergic rhinitis, bronchial asthma, and atopic dermatitis to be of significant importance, as it illustrates the phenomenon of multimorbidity of inflammatory conditions affecting the upper and lower respiratory tract.
鼻息肉常与支气管哮喘和鼻炎相关。症状的慢性特征、治疗后高复发率以及各种合并症，是显著影响诊断为此病患者生活质量的关键因素。
本研究旨在评估受检人群中鼻息肉的患病率，并评估鼻息肉（NP）与支气管哮喘（BA）、变应性鼻炎（AR）、非变应性鼻炎（NAR）和特应性皮炎（AD）可能的关联发生情况。
对18458名个体的研究组进行了欧洲社区呼吸健康调查（ECRHS）II问卷和儿童哮喘及变应性疾病国际研究（ISAAC）问卷调查，其中包括4473名6至7岁儿童（24.2%）、4675名13至14岁青少年（25.4%）和9310名20至44岁成年人（50.4%）。
受检组中鼻息肉的患病率为1.1%，共有204人报告患病。城市居民（191人（1.1%））报告鼻息肉的频率高于农村居民（13人（0.6%））。我们的研究表明鼻息肉的存在与哮喘以及变应性和非变应性鼻炎之间存在相关性。在评估的多种变应性疾病亚人群中，NP的最大危险因素是非变应性鼻炎和特应性皮炎共存（比值比=6.09；95%置信区间：3.4 - 10.93）。
在评估的波兰人群中，鼻息肉相对少见。尽管如此，我们认为它们与非变应性鼻炎、变应性鼻炎、支气管哮喘和特应性皮炎的共存具有重要意义，因为这说明了影响上、下呼吸道的炎症性疾病共病现象。
