Austin H, Cole P, McCraw D S
J Occup Med. 1986 Nov;28(11):1169-73.
A previous retrospective follow-up mortality study of white men employed at an oil refinery found an excess of leukemia deaths, especially of acute myeloid leukemia (AML). A case-control study was done to determine if the excess could be related to any particular jobs or departments at the refinery or to benzene exposures. The study includes 14 cases with leukemia (eight cases with AML) and 50 matched controls. No particular job or department was identified as the likely source of the excess leukemia deaths. Furthermore, the cases apparently had not been exposed to more benzene than had the controls. Thus, the reason for the excess leukemia at this refinery was not identified. The limitations of the study are discussed.
先前一项针对一家炼油厂就业白人男性的回顾性随访死亡率研究发现，白血病死亡人数过多，尤其是急性髓细胞白血病（AML）。开展了一项病例对照研究，以确定这种超额情况是否与炼油厂的任何特定工作或部门有关，或者与苯暴露有关。该研究包括14例白血病患者（8例AML患者）和50名匹配的对照。未发现特定的工作或部门是白血病死亡人数超额的可能来源。此外，病例接触的苯似乎并不比对照更多。因此，该炼油厂白血病超额的原因尚未明确。文中讨论了该研究的局限性。
