• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

内镜下止血喷雾治疗复杂内镜黏膜切除术或内镜黏膜下剥离术后难以控制的出血:2例报告

Endoscopic hemostatic spray for uncontrolled bleeding after complicated endoscopic mucosal resection or endoscopic submucosal dissection: a report of 2 cases.

作者信息

Hartz Kayla M, Lee Roland Y, Walsh Leonard T, Dixon Matthew E B, Moyer Matthew T

机构信息

Department of Internal Medicine, Penn State Health Milton S. Hershey Medical Center, Hershey, Pennsylvania.

Department of Surgery, Penn State Health Milton S. Hershey Medical Center, Hershey, Pennsylvania.

出版信息

VideoGIE. 2021 Jun 22;6(10):481-483. doi: 10.1016/j.vgie.2021.05.010. eCollection 2021 Oct.

DOI:10.1016/j.vgie.2021.05.010
PMID:34660948
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8503932/
Abstract

BACKGROUND AND AIMS

There is a significant bleeding risk after gastric endoscopic submucosal dissection (ESD) and EMR cases. This case series describes the use of an endoscopic hemostasis spray, which is not typically used to treat this type of bleeding, after multiple attempts with other modalities failed.

METHODS

We present 2 patient cases of ESD and EMR used to treat a gastric adenoma (case 1) and 2 gastric hyperplastic masses (case 2) with refractory bleeding after use of multiple other treatment modalities. Both patients were not surgical candidates because of their medical comorbidities.

RESULTS

Bleeding was eventually controlled with the use of endoscopic hemostasis spray after attempts were made using SB Knife Jr tip, Coagrasper Hemostatic Forceps, Argon Photocoagulation, and scope tamponade.

CONCLUSIONS

In very specific cases, endoscopic hemostasis spray may have some utility for refractory bleeding after dissection of gastric lesions. After using this spray, it became technically challenging to suture endoscopically because of the mud-like quality of the hemostasis material.

摘要

背景与目的

胃内镜黏膜下剥离术(ESD)和内镜黏膜切除术(EMR)后存在显著的出血风险。本病例系列描述了在多次尝试其他方法失败后,使用一种通常不用于治疗此类出血的内镜止血喷雾剂的情况。

方法

我们呈现了2例ESD和EMR患者病例,分别用于治疗胃腺瘤(病例1)和2个胃增生性肿块(病例2),在使用多种其他治疗方法后出现难治性出血。由于患者的内科合并症,这两名患者均不适合手术治疗。

结果

在尝试使用SB Knife Jr刀头、Coagrasper止血钳、氩离子凝固术和内镜压迫止血后,最终使用内镜止血喷雾剂控制了出血。

结论

在非常特殊的情况下,内镜止血喷雾剂可能对胃病变剥离后的难治性出血有一定作用。使用这种喷雾剂后,由于止血材料呈泥状,内镜缝合在技术上变得具有挑战性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f24/8503932/5e7271017514/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f24/8503932/24258f75a2cd/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f24/8503932/f4461879db66/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f24/8503932/5e7271017514/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f24/8503932/24258f75a2cd/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f24/8503932/f4461879db66/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f24/8503932/5e7271017514/gr3.jpg

相似文献

1
Endoscopic hemostatic spray for uncontrolled bleeding after complicated endoscopic mucosal resection or endoscopic submucosal dissection: a report of 2 cases.内镜下止血喷雾治疗复杂内镜黏膜切除术或内镜黏膜下剥离术后难以控制的出血:2例报告
VideoGIE. 2021 Jun 22;6(10):481-483. doi: 10.1016/j.vgie.2021.05.010. eCollection 2021 Oct.
2
Spray coagulation reduces the use of hemostatic forceps for intraoperative bleeding in gastric endoscopic submucosal dissection.喷雾凝固术减少了胃内镜黏膜下剥离术中用于处理术中出血的止血钳的使用。
JGH Open. 2024 Jul 19;8(7):e70002. doi: 10.1002/jgh3.70002. eCollection 2024 Jul.
3
Comparison of hemostatic ability between spray coagulation and forced coagulation modes in endoscopic submucosal dissection in patients with early gastric neoplasms: a study protocol for multicenter randomized controlled trial (Spray-G trial).比较内镜黏膜下剥离术在治疗早期胃肿瘤中喷雾凝血与强制凝血模式的止血效果:一项多中心随机对照试验的研究方案(Spray-G 试验)。
Trials. 2024 Jan 15;25(1):53. doi: 10.1186/s13063-023-07852-6.
4
Management of bleeding and artificial gastric ulcers associated with endoscopic submucosal dissection.内镜下黏膜下剥离术相关出血及人工胃溃疡的处理
World J Gastrointest Endosc. 2012 Jan 16;4(1):1-8. doi: 10.4253/wjge.v4.i1.1.
5
Efficacy of a new hemostatic forceps during gastric endoscopic submucosal dissection: A prospective randomized controlled trial.新型止血钳在胃内镜黏膜下剥离术中的疗效:一项前瞻性随机对照试验。
J Gastroenterol Hepatol. 2017 Apr;32(4):846-851. doi: 10.1111/jgh.13599.
6
A new technique for gastric endoscopic submucosal dissection: peroral traction-assisted endoscopic submucosal dissection.一种新的胃内镜黏膜下剥离术:经口牵引辅助内镜黏膜下剥离术。
Gastrointest Endosc. 2009 Jan;69(1):29-33. doi: 10.1016/j.gie.2008.03.1126.
7
Effect of spray COAG mode on hemostasis in colorectal endoscopic submucosal dissection using inverse probability of treatment weight analysis.采用治疗权重逆概率分析评估喷雾凝固模式在结直肠内镜黏膜下剥离术中的止血效果
DEN Open. 2024 Sep 16;5(1):e70008. doi: 10.1002/deo2.70008. eCollection 2025 Apr.
8
Endoscopic resection of sporadic duodenal adenomas: comparison of endoscopic mucosal resection (EMR) with hybrid endoscopic submucosal dissection (ESD) techniques and the risks of late delayed bleeding.散发性十二指肠腺瘤的内镜切除:内镜黏膜切除术(EMR)与内镜下黏膜下剥离术(ESD)混合技术的比较及迟发性出血风险
Surg Endosc. 2014 May;28(5):1594-600. doi: 10.1007/s00464-013-3356-y. Epub 2014 Jan 18.
9
Splash M-knife versus Flush Knife BT in the technical outcomes of endoscopic submucosal dissection for early gastric cancer: a propensity score matching analysis.早期胃癌内镜黏膜下剥离术技术结果中飞溅式M刀与Flush刀BT的比较:倾向评分匹配分析
BMC Gastroenterol. 2018 Feb 27;18(1):35. doi: 10.1186/s12876-018-0763-5.
10
Novel approaches to minimize intraoperative bleeding during endoscopic submucosal dissection of a large rectal lateral spreading tumor extended to the dentate line with internal hemorrhoids.在内镜下对延伸至齿状线并伴有内痔的大型直肠侧向发育肿瘤进行黏膜下剥离术时,尽量减少术中出血的新方法。
VideoGIE. 2021 May 28;6(8):344-346. doi: 10.1016/j.vgie.2021.04.005. eCollection 2021 Aug.

引用本文的文献

1
Hemostasis Strategies and Recent Advances in Nanomaterials for Hemostasis.止血策略及纳米材料在止血方面的最新进展
Molecules. 2023 Jul 7;28(13):5264. doi: 10.3390/molecules28135264.

本文引用的文献

1
ACG Clinical Guideline: Upper Gastrointestinal and Ulcer Bleeding.ACG 临床指南:上消化道和溃疡出血。
Am J Gastroenterol. 2021 May 1;116(5):899-917. doi: 10.14309/ajg.0000000000001245.
2
Risk of neoplastic change in large gastric hyperplastic polyps and recurrence after endoscopic resection.胃巨大增生性息肉中肿瘤性病变的风险和内镜切除后的复发。
Endoscopy. 2020 Jun;52(6):444-453. doi: 10.1055/a-1117-3166. Epub 2020 Mar 2.
3
Devices for endoscopic hemostasis of nonvariceal GI bleeding (with videos).非静脉曲张性胃肠道出血的内镜止血设备(附视频)
VideoGIE. 2019 Jun 27;4(7):285-299. doi: 10.1016/j.vgie.2019.02.004. eCollection 2019 Jul.
4
Complications related to gastric endoscopic submucosal dissection and their managements.与胃内镜黏膜下剥离术相关的并发症及其处理
Clin Endosc. 2014 Sep;47(5):398-403. doi: 10.5946/ce.2014.47.5.398. Epub 2014 Sep 30.
5
A lexicon for endoscopic adverse events: report of an ASGE workshop.内镜不良事件词汇表:美国胃肠内镜学会研讨会报告
Gastrointest Endosc. 2010 Mar;71(3):446-54. doi: 10.1016/j.gie.2009.10.027.
6
Endoscopic hemostatic devices.内镜止血设备。
Gastrointest Endosc. 2009 May;69(6):987-96. doi: 10.1016/j.gie.2008.12.251.
7
Risk factors for bleeding after endoscopic mucosal resection.内镜黏膜切除术后出血的危险因素。
World J Gastroenterol. 2005 Dec 14;11(46):7335-9. doi: 10.3748/wjg.v11.i46.7335.