Clinical Centre of Vojvodina, Hajduk Veljkova 1-7, 21000, Novi Sad, Serbia.
Faculty of medicine, University of Novi Sad, Novi Sad, Serbia.
Anaesthesist. 2021 Dec;70(Suppl 1):48-52. doi: 10.1007/s00101-021-01015-5. Epub 2021 Oct 18.
After laparoscopic cholecystectomy patients have moderate pain in the early postoperative period. According to several studies an erector spinae plane (ESP) block can be a valuable part of multimodal analgesia. Our intention was to evaluate how ESP block influences postoperative pain scores and opioid consumption after laparoscopic cholecystectomy.
This single-blinded, prospective, randomized study included 60 patients undergoing laparoscopic cholecystectomy to receive either bilateral ESP block at the Th 7 level (n = 30) with 20 ml of 0.25% levobupivacaine plus dexamethasone 2 mg per side, or standard multimodal analgesia (n = 30). Patients from the standard multimodal analgesia group received tramadol 100 mg at the end of the procedure. Postoperative analgesia for both groups was acetaminophen 1 g/8 h i.v. and ketorolac 30 mg/8 h. Tramadol 1 mg/kg was a rescue treatment for pain breakthrough (numeric rating scale/NRS ≥ 6) in both groups. Pain at rest was recorded at 10 min, 30 min, 2 h, 4 h, 8 h, 12 h and 24 h after surgery using NRS (0-10).
An ESP block significantly reduced postoperative pain scores compared to standard multimodal analgesia after 10 min (p = 0.011), 30 min (p = 0.004), 2 h (p = 0.011), 4 h (p = 0.003), 8 h (p = 0.013), 12 h (p = 0.004) and 24 h (p = 0.005). Tramadol consumption was significantly lower in the ESP group 25.02 ± 56.8g than in the standard analgesia group 208.3 ± 88.1g (p < 0.001).
An ESP block can provide superior postoperative analgesia and reduction in opioid requirement after laparoscopic cholecystectomy.
腹腔镜胆囊切除术后患者早期会有中度疼痛。根据几项研究,竖脊肌平面(ESP)阻滞可以成为多模式镇痛的重要组成部分。我们的目的是评估 ESP 阻滞对腹腔镜胆囊切除术后的术后疼痛评分和阿片类药物消耗的影响。
这是一项单盲、前瞻性、随机研究,纳入 60 例接受腹腔镜胆囊切除术的患者,分为双侧 ESP 阻滞组(n=30),在 Th7 水平每侧注射 20ml0.25%左旋布比卡因加 2mg 地塞米松,或标准多模式镇痛组(n=30)。标准多模式镇痛组的患者在手术结束时给予曲马多 100mg。两组术后镇痛均给予 1g/8h 静脉注射对乙酰氨基酚和 30mg/8h 静脉注射酮咯酸。曲马多 1mg/kg 为两组疼痛爆发(数字评分量表/NRS≥6)的解救治疗。术后 10min、30min、2h、4h、8h、12h 和 24h 时使用 NRS(0-10)记录静息时的疼痛。
与标准多模式镇痛相比,ESP 阻滞在术后 10min(p=0.011)、30min(p=0.004)、2h(p=0.011)、4h(p=0.003)、8h(p=0.013)、12h(p=0.004)和 24h(p=0.005)时显著降低了术后疼痛评分。ESP 组曲马多消耗量为 25.02±56.8g,明显低于标准镇痛组的 208.3±88.1g(p<0.001)。
ESP 阻滞可提供腹腔镜胆囊切除术后更好的术后镇痛效果,并减少阿片类药物的需求。