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HLA-A, -B, -C, -Bw4, Bw6 and -DR antigens are expressed on purified seminal cells other than spermatozoa.

作者信息

Rodríguez-Córdoba S, Regueiro J R, Arnaiz Villena A

出版信息

Scand J Immunol. 1986 Nov;24(5):545-8. doi: 10.1111/j.1365-3083.1986.tb02169.x.

DOI:10.1111/j.1365-3083.1986.tb02169.x
PMID:3466336
Abstract

HLA-A, HLA-B, HLA-C, HLA-Bw4, Bw6 and HLA-DR antigens have been detected on purified seminal cells than spermatozoa (SCnonSz) using specific absorptions. These results contrast with those obtained on spermatozoa, which only express significant amounts of HLA-A and HLA-B antigens, and which may be relevant to explain immunosuppressive alloimmunization in the acquired immunodeficiency syndrome (AIDS).

摘要

相似文献

1
HLA-A, -B, -C, -Bw4, Bw6 and -DR antigens are expressed on purified seminal cells other than spermatozoa.
Scand J Immunol. 1986 Nov;24(5):545-8. doi: 10.1111/j.1365-3083.1986.tb02169.x.
2
HLA-A and -B (but not -C, -Bw4, Bw6 or -DR antigens) are expressed on purified spermatozoa.
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3
Lack of HLA-molecules on human spermatozoa and in seminal plasma.人类精子及精浆中缺乏HLA分子。
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Characterization of a monoclonal anti-Bw4 antibody (Tü109): evidence for similar epitopes on the Bw4 and Bw6 antigens.一种抗Bw4单克隆抗体（Tü109）的特性：Bw4和Bw6抗原上相似表位的证据
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Bw4-reactive and Bw6-reactive antibodies recognize multiple distinct HLA structures that partially overlap in the alpha-1 helix.Bw4反应性抗体和Bw6反应性抗体识别多种不同的HLA结构，这些结构在α-1螺旋中部分重叠。
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The primary structure of HLA-A32 suggests a region involved in formation of the Bw4/Bw6 epitopes.HLA - A32的一级结构表明存在一个参与Bw4/Bw6表位形成的区域。
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