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胸段硬膜外镇痛用于腰骶部脊柱手术:一项随机病例对照研究。

Thoracic Epidural Analgesia for Lumbosacral Spine Surgery: A Randomized, Case-Control Study.

作者信息

Kour Loveleen, Sharma Nandita, Dogra Disha

机构信息

Department of Anaesthesia and Intensive Care, GMC, Jammu, Jammu and Kashmir, India.

出版信息

Anesth Essays Res. 2021 Jan-Mar;15(1):119-125. doi: 10.4103/aer.aer_77_21. Epub 2021 Aug 30.

DOI:10.4103/aer.aer_77_21
PMID:34667358
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8462426/
Abstract

BACKGROUND

Traditional analgesics such as diclofenac and celecoxib have long been used in lumbosacral spine surgeries. Recently, preemptive single-shot caudal analgesia has been investigated by some workers with favorable results. We hypothesized that the thoracic route would not only allow preemptive but also postoperative analgesia through catheter insertion.

AIM

We aimed at studying the feasibility and efficacy of thoracic epidural analgesia (TEA) in lumbosacral spine surgeries.

SETTINGS AND DESIGN

This was a prospective, randomized, controlled study that comprised 60 American Society of Anesthesiologist (ASA) Physical Status I and II patients posted for lumbosacral spine surgeries.

MATERIALS AND METHODS

Sixty ASA I and II patients were randomly divided into two groups: Group T - TEA was given using 0.2% ropivacaine 10 mL preemptive and postoperatively. Group C patients were given analgesia with intramuscular diclofenac 75 mg. Hemodynamic parameters, postoperative Visual Analog Scale scores, and neurological complications were noted.

STATISTICAL ANALYSIS

Student's independent -test for comparing the continuous variables and Chi-square test for the categorical variables. Kruskal-Wallis test was used for postoperative pain data.

RESULTS

Duration and quality of analgesia were superior in Group T. There were more hemodynamic alterations in Group C but no neurological complication in any patient.

CONCLUSION

TEA proves to be an effective analgesic technique for lumbosacral spine surgeries.

摘要

背景

传统镇痛药如双氯芬酸和塞来昔布长期用于腰骶部脊柱手术。最近,一些研究人员对单次预防性骶管镇痛进行了研究,结果良好。我们推测,经胸途径不仅可以实现预防性镇痛,还可以通过插入导管实现术后镇痛。

目的

我们旨在研究胸段硬膜外镇痛(TEA)在腰骶部脊柱手术中的可行性和有效性。

设置与设计

这是一项前瞻性、随机、对照研究,纳入了60例拟行腰骶部脊柱手术的美国麻醉医师协会(ASA)身体状况I级和II级患者。

材料与方法

60例ASA I级和II级患者随机分为两组:T组——术前和术后均使用10 mL 0.2%罗哌卡因进行TEA。C组患者给予75 mg肌内注射双氯芬酸镇痛。记录血流动力学参数、术后视觉模拟量表评分和神经并发症。

统计分析

采用学生独立t检验比较连续变量,采用卡方检验比较分类变量。采用Kruskal-Wallis检验分析术后疼痛数据。

结果

T组镇痛持续时间和质量更佳。C组血流动力学改变更多,但所有患者均未出现神经并发症。

结论

TEA被证明是腰骶部脊柱手术有效的镇痛技术。

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本文引用的文献

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Dexmedetomidine versus fentanyl added to bupivacaine for epidural analgesia in combination with general anesthesia for elective lumbar disc operations: A prospective, randomized double-blinded study.右美托咪定与芬太尼添加于布比卡因用于择期腰椎间盘手术硬膜外镇痛联合全身麻醉的前瞻性随机双盲研究。
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Effects of thoracic epidural anesthesia/analgesia on the stress response, pain relief, hospital stay, and treatment costs of patients with esophageal carcinoma undergoing thoracic surgery: A single-center, randomized controlled trial.胸段硬膜外麻醉/镇痛对食管癌胸科手术患者应激反应、疼痛缓解、住院时间及治疗费用的影响:一项单中心随机对照试验。
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Pre-emptive caudal epidural analgesia with ropivacaine for lumbosacral spine surgery: A randomized case control study.罗哌卡因用于腰骶部脊柱手术的预防性骶管硬膜外镇痛:一项随机病例对照研究。
J Anaesthesiol Clin Pharmacol. 2018 Apr-Jun;34(2):237-241. doi: 10.4103/joacp.JOACP_72_17.
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Preemptive Caudal Ropivacaine: An Effective Analgesic during Degenerative Lumbar Spine Surgery.预防性骶管罗哌卡因:在退变性腰椎手术中一种有效的镇痛方法。
Asian Spine J. 2017 Feb;11(1):113-119. doi: 10.4184/asj.2017.11.1.113. Epub 2017 Feb 17.
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A comparison of thoracic spinal anesthesia with low-dose isobaric and low-dose hyperbaric bupivacaine for orthopedic surgery: A randomized controlled trial.低剂量等比重和低剂量重比重布比卡因用于骨科手术的胸椎脊髓麻醉比较:一项随机对照试验。
Anesth Essays Res. 2014 Jan-Apr;8(1):26-31. doi: 10.4103/0259-1162.128900.
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General anesthesia versus segmental thoracic or conventional lumbar spinal anesthesia for patients undergoing laparoscopic cholecystectomy.全身麻醉与节段性胸椎或传统腰椎脊髓麻醉用于接受腹腔镜胆囊切除术的患者。
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