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Proc Natl Acad Sci U S A. 2020 Dec 1;117(48):30547-30553. doi: 10.1073/pnas.2013182117. Epub 2020 Nov 9.
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Interference between rhinovirus and influenza A virus: a clinical data analysis and experimental infection study.鼻病毒和甲型流感病毒的相互干扰:临床数据分析和实验感染研究。
Lancet Microbe. 2020 Oct;1(6):e254-e262. doi: 10.1016/s2666-5247(20)30114-2. Epub 2020 Sep 5.
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Genotypic diversity, circulation patterns and co-detections among rhinoviruses in Queensland, 2001.2001年昆士兰鼻病毒的基因多样性、传播模式及共同检测情况
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Relationship between Influenza Vaccination Coverage Rate and COVID-19 Outbreak: An Italian Ecological Study.流感疫苗接种覆盖率与新冠疫情之间的关系:一项意大利生态学研究。
Vaccines (Basel). 2020 Sep 16;8(3):535. doi: 10.3390/vaccines8030535.
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Comparing SARS-CoV-2 with SARS-CoV and influenza pandemics.比较 SARS-CoV-2 与 SARS-CoV 和流感大流行。
Lancet Infect Dis. 2020 Sep;20(9):e238-e244. doi: 10.1016/S1473-3099(20)30484-9. Epub 2020 Jul 3.
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新冠病毒与季节性流感:二者不可共存。

COVID-19 and Seasonal Influenza: No Room for Two.

作者信息

Spantideas Nikolaos, Bougea Anastasia M, Drosou Eirini G, Khanderia Neha, Rai Summina

机构信息

ENT, Northwick Park Hospital, London, GBR.

Neurology, Aeginition Hospital, National and Kapodistrian University of Athens, Athens, GRC.

出版信息

Cureus. 2021 Sep 15;13(9):e18007. doi: 10.7759/cureus.18007. eCollection 2021 Sep.

DOI:10.7759/cureus.18007
PMID:34667682
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8516323/
Abstract

Objective With the outbreak of COVID-19 in December 2019 fears were expressed for a possible twindemic in the coming flu seasons. Fortunately, this was not the case for the 2019-2020 and 2020-2021 flu seasons as flu showed very low historical rates during these periods. The objective of our study was to look at the existing flu data for the 2019-2021 period and analyze possible reasons for the near absence of seasonal flu. Methods We performed retrospective surveillance regarding seasonal influenza rates for the years 2019-2021, the years that the COVID-19 was present. Epidemiological data concerning seasonal influenza for the years 2019-2021 were collected and analyzed Results Extremely low numbers of flu cases were reported in FluNet, FluView, and TESSy influenza surveillance systems during the years 2019, 2020, and 2021 compared to previous years prior to COVID-19. Conclusions A twindemic outbreak during the 2019-2021 flu seasons did not occur despite expressed concerns. The worldwide implementation of mitigation measures for individuals and communities to control severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission, the increased flu vaccination rate, the virus interference and the lower rate of testing for flu are the main reasons for the marked decrease in reported flu cases during 2019-2021 flu seasons.

摘要

目的 随着2019年12月新型冠状病毒肺炎(COVID-19)的爆发,人们担心在即将到来的流感季节可能会出现双流行。幸运的是,在2019-2020年和2020-2021年流感季节并非如此,因为在此期间流感发病率处于历史极低水平。我们研究的目的是查看2019-2021年期间现有的流感数据,并分析季节性流感几乎消失的可能原因。方法 我们对2019-2021年(即COVID-19出现的年份)的季节性流感发病率进行了回顾性监测。收集并分析了2019-2021年有关季节性流感的流行病学数据。结果 与COVID-19之前的前几年相比,2019年、2020年和2021年在FluNet、FluView和TESSy流感监测系统中报告的流感病例数极少。结论 尽管有人担心,但在2019-2021年流感季节并未出现双流行疫情。全球范围内为个人和社区实施的控制严重急性呼吸综合征冠状病毒2(SARS-CoV-2)传播的缓解措施、流感疫苗接种率的提高、病毒干扰以及流感检测率的降低是2019-2021年流感季节报告的流感病例显著减少的主要原因。