巴西 HIV 感染孕妇李斯特菌血清流行率。
Seroprevalence of Listeria monocytogenes in HIV infected pregnant women from Brazil.
机构信息
Universidade Federal do Rio de Janeiro, Instituto de Puericultura e Pediatria Martagão, Departamento de Medicina Preventiva, Rio de Janeiro, RJ, Brazil.
LABZOO-FIOCRUZ - Listeria Reference Laboratory, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brazil.
出版信息
Braz J Infect Dis. 2021 Nov-Dec;25(6):101635. doi: 10.1016/j.bjid.2021.101635. Epub 2021 Oct 19.
OBJECTIVE
To describe the prevalence and factors associated with serologic response to Listeria monocytogenes in HIV infected and uninfected pregnant women in Brazil.
METHODS
Cross-sectional study, pregnant women after 14 weeks of gestational age were enrolled. Positive serologic test for L. monocytogenes was defined as titers >1:80 (agglutination test). Comparisons were performed using logistic regression.
RESULTS
A total of 213 women were enrolled, 73 (34%) were HIV infected. 55 women were seroreactive for L. monocytogenes, 27 (37%) HIV-infected and 28 (20%) HIV-uninfected (p < 0.01). Considering the diet record, white cheese consumption was associated with seroreactivity (p < 0.01). In the group of pregnant women living with HIV, the variables associated with L. monocytogenes positive serology were: lower CD4+ cells count at study entry OR=4.8 (95%CI=1.1-19.8) and having neonates admitted to the intensive care unit OR=5.9 (95%CI=1.01-34.9).
CONCLUSION
Positive serology for Listeria monocytogenes was associated with HIV infection. Brazilian women should avoid white cheese during pregnancy.
目的
描述巴西 HIV 感染和未感染孕妇李斯特菌血清学反应的流行情况及相关因素。
方法
这是一项横断面研究，纳入了妊娠 14 周后的孕妇。李斯特菌血清学阳性检测定义为滴度>1:80（凝集试验）。采用 logistic 回归进行比较。
结果
共纳入 213 名孕妇，73 名（34%）感染了 HIV。55 名孕妇对李斯特菌呈血清学反应，27 名（37%）HIV 感染，28 名（20%）HIV 未感染（p<0.01）。考虑饮食记录，食用白奶酪与血清反应性相关（p<0.01）。在感染 HIV 的孕妇组中，与李斯特菌阳性血清学相关的变量为：研究入组时 CD4+细胞计数较低 OR=4.8（95%CI=1.1-19.8）和新生儿入住重症监护病房 OR=5.9（95%CI=1.01-34.9）。
结论
李斯特菌血清学阳性与 HIV 感染相关。巴西孕妇在怀孕期间应避免食用白奶酪。
Zotero 插件