Gálvez María Victoria de, Aguilera José, Leal María, Sánchez-Roldán Cristina, Herrera-Ceballos Enrique
Photobiological Dermatology Laboratory, Medical Research Center, Department of Dermatology and Medicine, Faculty of Medicine, University of Malaga, Málaga, Spain.
Dermatology Service, Universitary Clinical Hospital Virgen de la Victoria, Málaga, Spain.
Photodermatol Photoimmunol Photomed. 2022 May;38(3):250-258. doi: 10.1111/phpp.12745. Epub 2021 Nov 23.
Sunscreens are widely used to protect the skin against the harmful effects of solar radiation. It is not known whether solar protection factor of a sunscreen is altered by the concomitant use of other cosmetic products.
The aim of this study was to analyze changes in the protective effect of different commercial and ISO standards sunscreens with high SPF applied shortly before and after application of non-sunscreens galenic formulas type moisturizing creams.
ISO 24444:2019 standard sunscreens, which claimed SPF 16 and 63, as well as 4 different claimed SPF 50 and 50+ commercial sunscreens were prepared and applied in different sequential order to the back of 25 volunteers and compared with different commercial moisturizing formulas. Ultraviolet (UV) reflectance photography followed by image analysis was used to compare untreated skin and skin treated with moisturizing creams alone and combined with sunscreens.
The UV reflectance analysis showed no significant changes of the skin color reflectance treated with moisturizing cream compared with untreated skin. Application of the sunscreen formulations were associated with a 35% - 70% decrease in color related to the in vivo expected SPF, indicating significant UV absorption for all sunscreen formulas. All standard and commercial sunscreens showed no significant differences in UV reflection color level when combined with the different moisturizing creams applied before or after the sunscreen.
Effectiveness of low- and high-protection sunscreens were not altered by the concomitant use of a moisturizing creams applied shortly before and after the sunscreens.
防晒霜被广泛用于保护皮肤免受太阳辐射的有害影响。目前尚不清楚防晒霜的防晒系数是否会因同时使用其他化妆品而改变。
本研究的目的是分析在使用非防晒类盖伦制剂型保湿霜之前和之后不久涂抹的不同商业和ISO标准的高防晒系数防晒霜的防护效果变化。
制备了宣称防晒系数为16和63的ISO 24444:2019标准防晒霜，以及4种宣称防晒系数为50和50+的不同商业防晒霜，并以不同的顺序涂抹在25名志愿者的背部，与不同的商业保湿配方进行比较。采用紫外线（UV）反射摄影及图像分析来比较未处理的皮肤、单独使用保湿霜处理的皮肤以及与防晒霜联合使用的皮肤。
紫外线反射分析显示，与未处理的皮肤相比，使用保湿霜处理的皮肤颜色反射率没有显著变化。涂抹防晒霜配方后，与体内预期防晒系数相关的颜色降低了35% - 70%，表明所有防晒霜配方都有显著的紫外线吸收。当与在防晒霜之前或之后涂抹 的不同保湿霜联合使用时，所有标准和商业防晒霜在紫外线反射颜色水平上均无显著差异。
在防晒霜之前和之后不久使用保湿霜，不会改变低防护和高防护防晒霜的有效性。
