Suppr超能文献

SARS-CoV-2 大流行对避孕措施和妊娠意愿的影响:一项针对英国人口的全国前瞻性队列研究。

Impact of the SARS-CoV-2 pandemic on access to contraception and pregnancy intentions: a national prospective cohort study of the UK population.

机构信息

Reproductive Medicine Unit, University College London Hospitals NHS Foundation Trust, London, UK.

EGA Institute for Womens Health, University College London Medical School, London, UK.

出版信息

BMJ Sex Reprod Health. 2022 Jan;48(1):60-65. doi: 10.1136/bmjsrh-2021-201164. Epub 2021 Oct 21.

Abstract

OBJECTIVE

Evaluate the impact of the COVID-19 pandemic on access to contraception and pregnancy intentions.

DESIGN

Nationwide prospective cohort study.

SETTING

United Kingdom.

PARTICIPANTS

Women in the UK who were pregnant between 24 May and 31 December 2020.

MAIN OUTCOME MEASURES

Access to contraception and level of pregnancy intentions, using the London Measure of Unplanned Pregnancy (LMUP) in women whose last menstrual period was before or after 1 April 2020. While the official date of the first UK lockdown was 23 March, we used 1 April to ensure that those in the post-lockdown group would have faced restrictions in the month that they conceived.

RESULTS

A total of 9784 women enrolled in the cohort: 4114 (42.0%) conceived pre-lockdown and 5670 (58.0%) conceived post-lockdown. The proportion of women reporting difficulties accessing contraception was higher in those who conceived after lockdown (n=366, 6.5% vs n=25, 0.6%, p<0.001) and continued to rise from March to September 2020. After adjusting for confounders, women were nine times more likely to report difficulty accessing contraception after lockdown (adjusted odds ratio (aOR) 8.96, 95% CI 5.89 to 13.63, p<0.001). There is a significant difference in the levels of pregnancy planning, with higher proportions of unplanned (n=119, 2.1% vs n=55, 1.3%) and ambivalent pregnancies (n=1163, 20.5% vs n=663, 16.1%) and lower proportions of planned pregnancies (n=4388, 77.4% vs n=3396, 82.5%) in the post-lockdown group (p<0.001). After adjusting for confounders, women who conceived after lockdown were still significantly less likely to have a planned pregnancy (aOR 0.88, 95% CI 0.79 to 0.98, p=0.025).

CONCLUSIONS

Access to contraception in the UK has become harder during the COVID-19 pandemic and the proportion of unplanned pregnancies has almost doubled.

摘要

目的

评估 COVID-19 大流行对避孕措施的可及性和妊娠意愿的影响。

设计

全国性前瞻性队列研究。

地点

英国。

参与者

2020 年 5 月 24 日至 12 月 31 日期间怀孕的英国妇女。

主要观察指标

使用伦敦意外妊娠量表(London Measure of Unplanned Pregnancy,LMUP)评估在 2020 年 4 月 1 日前或之后最后一次月经的女性的避孕措施可及性和妊娠意愿水平。虽然英国第一次封锁的官方日期是 3 月 23 日,但我们使用 4 月 1 日来确保那些处于封锁后组的女性在受孕的那个月会面临限制。

结果

共有 9784 名妇女入组该队列:4114 名(42.0%)在封锁前受孕,5670 名(58.0%)在封锁后受孕。在封锁后受孕的女性中,报告避孕措施获取困难的比例更高(n=366,6.5%vsn=25,0.6%,p<0.001),并且从 2020 年 3 月到 9 月持续上升。调整混杂因素后,与封锁前受孕的女性相比,封锁后受孕的女性报告避孕措施获取困难的可能性高出 9 倍(调整后的优势比(adjusted odds ratio,aOR)8.96,95%置信区间(confidence interval,CI)5.89 至 13.63,p<0.001)。妊娠计划的水平存在显著差异,封锁后组的无计划妊娠(n=119,2.1%vsn=55,1.3%)和矛盾妊娠(n=1163,20.5%vsn=663,16.1%)比例更高,计划妊娠(n=4388,77.4%vsn=3396,82.5%)比例更低(p<0.001)。调整混杂因素后,与封锁前受孕的女性相比,封锁后受孕的女性仍不太可能有计划妊娠(aOR 0.88,95%CI 0.79 至 0.98,p=0.025)。

结论

在 COVID-19 大流行期间,英国的避孕措施可及性变得更加困难,无计划妊娠的比例几乎翻了一番。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e2e/8762005/17bfd3588700/bmjsrh-2021-201164f01.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验