Assay Development and Screening Platform, Helmholtz Zentrum München, Neuherberg, Germany.
Department of Biological Sciences, Columbia University, New York, USA.
Nat Chem Biol. 2021 Nov;17(11):1113-1116. doi: 10.1038/s41589-021-00853-z.
Ferroptosis is a regulated form of non-apoptotic cell death implicated in pathological settings. To be exploited clinically, ferroptosis requires reagents that unequivocally detect ferroptosis in human and animal tissues. Such tools may enable development of ferroptosis-based medicines for diverse diseases.
铁死亡是一种与病理状态相关的受调控的非细胞凋亡性的细胞死亡方式。为了能够在临床上加以利用，铁死亡需要有能够明确检测人和动物组织中铁死亡的试剂。此类工具的开发可能有助于研发基于铁死亡的多种疾病治疗药物。
