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铁死亡:又一种程序性细胞死亡方式。

Ferroptosis: Yet Another Way to Die.

机构信息

Commonwealth Scientific and Industrial Research Organisation (CSIRO) Agriculture and Food, Brisbane, Queensland, Australia; Queensland Alliance for Agriculture and Food Innovation (QAAFI), The University of Queensland, Brisbane, Queensland, Australia.

Commonwealth Scientific and Industrial Research Organisation (CSIRO) Agriculture and Food, Brisbane, Queensland, Australia.

出版信息

Trends Plant Sci. 2019 Jun;24(6):479-481. doi: 10.1016/j.tplants.2019.03.005. Epub 2019 Mar 23.

DOI:10.1016/j.tplants.2019.03.005
PMID:30910286
Abstract

Cell death is one of the most fundamental biological processes operating in multicellular organisms. Recent research highlighted here [Distéfano et al. (J. Cell Biol. 2017:216;463-476) and Dangol et al. (Plant Cell 2019:31;189-209)] revealed an iron- and ROS-dependent cell death phenomenon called ferroptosis in plants. Features distinguishing ferroptosis from other cell death events and how ferroptosis can be exploited to improve plant performance are discussed.

摘要

细胞死亡是多细胞生物中最基本的生物学过程之一。本文[Distéfano 等人(细胞生物学杂志,2017 年;216:463-476)和 Dangol 等人(植物细胞,2019 年;31:189-209)]强调了最近的研究发现,植物中存在一种依赖铁和 ROS 的细胞死亡现象,称为铁死亡。本文讨论了铁死亡与其他细胞死亡事件的区别特征,以及如何利用铁死亡来提高植物的性能。

相似文献

1
Ferroptosis: Yet Another Way to Die.铁死亡:又一种程序性细胞死亡方式。
Trends Plant Sci. 2019 Jun;24(6):479-481. doi: 10.1016/j.tplants.2019.03.005. Epub 2019 Mar 23.
2
Ferroptosis: Role of lipid peroxidation, iron and ferritinophagy.铁死亡:脂质过氧化、铁和铁蛋白自噬的作用。
Biochim Biophys Acta Gen Subj. 2017 Aug;1861(8):1893-1900. doi: 10.1016/j.bbagen.2017.05.019. Epub 2017 May 24.
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Ferroptosis as a New Type of Cell Death and its Role in Cancer Treatment.铁死亡作为一种新型细胞死亡方式及其在癌症治疗中的作用
Klin Onkol. 2018 Winter;31(Suppl 2):21-26. doi: 10.14735/amko20182S21.
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Heat stress induces ferroptosis-like cell death in plants.热胁迫诱导植物发生铁死亡样细胞死亡。
J Cell Biol. 2017 Feb;216(2):463-476. doi: 10.1083/jcb.201605110. Epub 2017 Jan 18.
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Ferroptosis in plants: triggers, proposed mechanisms, and the role of iron in modulating cell death.植物中的铁死亡:触发因素、拟议机制以及铁在调节细胞死亡中的作用。
J Exp Bot. 2021 Mar 17;72(6):2125-2135. doi: 10.1093/jxb/eraa425.
6
Reactive Oxygen Species-Induced Lipid Peroxidation in Apoptosis, Autophagy, and Ferroptosis.活性氧诱导的细胞凋亡、自噬和铁死亡中的脂质过氧化作用。
Oxid Med Cell Longev. 2019 Oct 13;2019:5080843. doi: 10.1155/2019/5080843. eCollection 2019.
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Iron accumulation, glutathione depletion, and lipid peroxidation must occur simultaneously during ferroptosis and are mutually amplifying events.铁积累、谷胱甘肽耗竭和脂质过氧化在铁死亡过程中必须同时发生,且是相互放大的事件。
Med Hypotheses. 2017 Apr;101:69-74. doi: 10.1016/j.mehy.2017.02.017. Epub 2017 Feb 28.
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Ferroptosis is an autophagic cell death process.铁死亡是一种自噬性细胞死亡过程。
Cell Res. 2016 Sep;26(9):1021-32. doi: 10.1038/cr.2016.95. Epub 2016 Aug 12.
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Ferroptosis is associated with oxygen-glucose deprivation/reoxygenation-induced Sertoli cell death.铁死亡与氧葡萄糖剥夺/再复氧诱导的支持细胞死亡有关。
Int J Mol Med. 2018 May;41(5):3051-3062. doi: 10.3892/ijmm.2018.3469. Epub 2018 Feb 7.
10
Ferroptosis and autophagy induced cell death occur independently after siramesine and lapatinib treatment in breast cancer cells.在乳腺癌细胞中,西拉米辛和拉帕替尼治疗后,铁死亡和自噬诱导的细胞死亡独立发生。
PLoS One. 2017 Aug 21;12(8):e0182921. doi: 10.1371/journal.pone.0182921. eCollection 2017.

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Front Pharmacol. 2025 Apr 16;16:1552251. doi: 10.3389/fphar.2025.1552251. eCollection 2025.
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RNA binding protein ALYREF regulates ferroptosis to facilitate LUAD growth and metastasis via promoting SLC7A11 mRNA stability.RNA结合蛋白ALYREF通过促进SLC7A11 mRNA稳定性来调节铁死亡,以促进肺腺癌的生长和转移。
Sci Rep. 2025 Jan 8;15(1):1351. doi: 10.1038/s41598-024-83276-9.
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Mechanism and application prospect of ferroptosis inhibitors in improving osteoporosis.
铁死亡抑制剂改善骨质疏松症的机制及应用前景
Front Endocrinol (Lausanne). 2024 Dec 13;15:1492610. doi: 10.3389/fendo.2024.1492610. eCollection 2024.
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Transcription factor NF-E2-related factor 2 plays a critical role in acute lung injury/acute respiratory distress syndrome (ALI/ARDS) by regulating ferroptosis.转录因子NF-E2相关因子2通过调节铁死亡在急性肺损伤/急性呼吸窘迫综合征(ALI/ARDS)中起关键作用。
PeerJ. 2024 Jul 30;12:e17692. doi: 10.7717/peerj.17692. eCollection 2024.
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Ecophysiological responses of populations to a tidal flat gradient in the Yangtze River Estuary, China.中国长江口潮滩梯度上种群的生理生态响应
Front Plant Sci. 2024 Apr 30;15:1326345. doi: 10.3389/fpls.2024.1326345. eCollection 2024.
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Understanding the Novel Approach of Nanoferroptosis for Cancer Therapy.了解纳米铁死亡用于癌症治疗的新方法。
Nanomicro Lett. 2024 May 2;16(1):188. doi: 10.1007/s40820-024-01399-0.
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Delineation and authentication of ferroptosis genes in ventilator-induced lung injury.呼吸机诱导肺损伤中铁死亡基因的描绘和鉴定。
BMC Med Genomics. 2024 Jan 23;17(1):31. doi: 10.1186/s12920-024-01804-y.
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Regulatory roles of copper metabolism and cuproptosis in human cancers.铜代谢和铜死亡在人类癌症中的调控作用。
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Transcriptome Analysis of Over-Expressing Wheat Roots Reveals Ferroptosis-like Cell Death in Heat Stress Recovery.转录组分析过量表达的小麦根系揭示了热胁迫恢复过程中的铁死亡样细胞死亡。
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