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经视频辅助肛瘘治疗向挂线切开术转换的预测风险因素。

Predictive Risk Factors of the Conversion from Video-Assisted Treatment of Anal Fistula to Seton Fistulotomy.

机构信息

Department of Colorectal Surgery, Beijing Erlonglu Hospital, Beijing, People's Republic of China.

出版信息

J Laparoendosc Adv Surg Tech A. 2022 Jun;32(6):634-638. doi: 10.1089/lap.2021.0425. Epub 2021 Oct 22.

Abstract

To identify the risk factors of converting from video-assisted anal fistula treatment (VAAFT) to seton fistulotomy. A total of 180 patients registered to undergo VAAFT between January 2016 and June 2020 at the Erlonglu Hospital. Intraoperative examination of the fistula tract revealed that the patients were assigned to undergo the VAAFT operation and seton fistulotomy. Among 180 patients aged 37 (±10.4) years who underwent intraoperative examination of the fistula tract, 101 completed the standard VAAFT and 79 converted to seton fistulotomy. Univariate analyses revealed that age, necrotic cavity diameter ≥1 cm, scars at the anal entrance, tissue edema, Parks classification, fistula stenosis, and fistula branches were significantly different between the VAAFT and converted groups ( < .05). Multivariate analysis revealed a significant correlation between the risk of surgery conversion and the presence of necrotic cavity with a diameter of ≥1 cm (odds ratio [OR]: 3.668, 95% confidence interval [CI]: 1.366-9.853,  = .01), scars at the anal entrance (OR: 9.462, 95% CI: 1.562-57.32,  = .014), fistula stenosis (OR: 25.14, 95% CI: 5.211-121.3,  < .001), and fistula branches (OR: 2.90, 95% CI: 1.088-7.73,  = .033). The nomogram based on the logistic model was fitted with high accuracy and area under curve of 0.793 (95% CI: 0.726-0.861). The independent risk factors of conversion from surgery for VAAFT to seton fistulotomy were the presence of necrotic cavity with a diameter of ≥1 cm, scars at the anal entrance, fistula stenosis, and fistula branches. The protocol of this systematic review was registered a priori in the Chinese Clinical Trial Registry (ChiCTR) under the registration number of ChiCTR1900022810.

摘要

为了确定从视频辅助肛瘘治疗(VAAFT)转为挂线切开术的风险因素。2016 年 1 月至 2020 年 6 月,共有 180 名患者在二龙路医院接受 VAAFT 治疗。术中检查瘘管发现,患者被分配接受 VAAFT 手术和挂线切开术。在 180 名年龄 37(±10.4)岁接受术中瘘管检查的患者中,101 名完成了标准的 VAAFT,79 名转为挂线切开术。单因素分析显示,VAAFT 组和转化组在年龄、坏死腔直径≥1cm、肛门入口处瘢痕、组织水肿、Parks 分类、瘘管狭窄和瘘管分支方面差异有统计学意义( < .05)。多因素分析显示,手术转换的风险与直径≥1cm 的坏死腔的存在显著相关(优势比[OR]:3.668,95%置信区间[CI]:1.366-9.853,  = .01),肛门入口处瘢痕(OR:9.462,95% CI:1.562-57.32,  = .014),瘘管狭窄(OR:25.14,95% CI:5.211-121.3,  < .001)和瘘管分支(OR:2.90,95% CI:1.088-7.73,  = .033)。基于逻辑模型拟合的列线图具有较高的准确性,曲线下面积为 0.793(95%CI:0.726-0.861)。VAAFT 手术转为挂线切开术的独立危险因素为坏死腔直径≥1cm、肛门入口处瘢痕、瘘管狭窄和瘘管分支。本系统评价的方案预先在中国临床试验注册中心(ChiCTR)注册,注册号为 ChiCTR1900022810。

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