Uzer Fatih, Cilli Aykut
Department of Pulmonology, Akdeniz University School of Medicine, Antalya, Turkey.
Med Gas Res. 2022 Apr-Jun;12(2):67-68. doi: 10.4103/2045-9912.326003.
A 76-year-old female received a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine (CoronaVac, Sinovac, Beijing, China) and subsequently experienced chest discomfort. A computed tomography performed 1 day after vaccination showed multiple infiltrations in both lungs and ground-glass shadows in both lung fields. Her fingertip oxygen saturation was 81% and there was widespread wheezing on physical examination. Based on these findings, the patient was hospitalized with a preliminary diagnosis of drug-induced pneumonitis and acute asthma exacerbation due to a SARS-CoV-2 vaccine. During her hospitalization, 40 mg/d systemic steroid, 4 times a day salbutamol nebulized, 2 L/min inhaled oxygen therapy and 400 mg/d moxifloxacin intravenous were administered for 5 days. One month later, the thorax computed tomography scan revealed that the previous findings were almost completely regressed.
一名76岁女性接种了严重急性呼吸综合征冠状病毒2（SARS-CoV-2）疫苗（科兴中维的克尔来福，中国北京），随后出现胸部不适。接种疫苗1天后进行的计算机断层扫描显示双肺多发浸润及双肺野磨玻璃影。她的指尖血氧饱和度为81%，体格检查发现广泛哮鸣音。基于这些发现，患者因SARS-CoV-2疫苗导致药物性肺炎和急性哮喘加重而住院。住院期间，给予40mg/d全身用类固醇、每日4次沙丁胺醇雾化、2L/min吸氧治疗以及400mg/d莫西沙星静脉滴注，持续5天。1个月后，胸部计算机断层扫描显示先前的表现几乎完全消退。
