Cheng Chia-Hsiung, Lin Szu-Hung, Wu Ching-Yi, Liao Yi-Han, Chang Ku-Chou, Hsieh Yu-Wei
Department of Occupational Therapy, Graduate Institute of Behavioral Sciences, Chang Gung University, Taoyuan City, Taiwan.
Laboratory of Brain Imaging and Neural Dynamics (BIND Lab), Chang Gung University, Taoyuan City, Taiwan.
Front Neurosci. 2020 Jan 14;13:1363. doi: 10.3389/fnins.2019.01363. eCollection 2019.
We differentiated the influence of mirror-induced visual conflicts on the perceptual-attention-motor control process by examining the variation of primary motor cortex (M1) activities and the functional connectivity among five brain regions associated with perceptual, motor, and attentional processes. Magnetoencephalography (MEG) was recorded under three conditions: both hands kept stationary with the forearms supinated (resting condition), in-phase bimanual movements with congruent visual feedback [symmetry (Sym) condition], and out-of-phase bimanual movements with incongruent visual feedback [asymmetry (Asy) condition]. We found that compared with the resting state, the decrease in beta oscillation was greater in the Sym than in the Asy condition, suggesting a greater activation of M1 when implementing hand movement without visual conflict. The results of functional connectivity patterns showed that the alpha band functional connectivity between V1 and superior temporal gyrus (STG) and the gamma band functional connectivity between the precuneus and posterior cingulate cortex (PCC) triggered greater or slightly greater coherence strength in the Asy condition than in the Sym condition. However, the beta band functional connectivity showed no difference between the two conditions in all pairs of the brain regions. These findings confirm and extend the previous findings to provide evidence that mirror visual feedback engages the functional networks associated with the perceptual-attentional process and triggers M1 activation, although the M1 activation is functionally independent of other brain regions unrelated to motor function. In summary, this study demonstrated a concrete functional connectivity pattern for motor control in the face of visual conflicts, and providing a foundation for future research to examine the dynamic functional networks of mirror illusion in motor control.
我们通过检查初级运动皮层（M1）活动的变化以及与感知、运动和注意力过程相关的五个脑区之间的功能连接，来区分镜像诱导的视觉冲突对感知-注意力-运动控制过程的影响。在三种条件下记录脑磁图（MEG）：双手前臂旋后保持静止（静息状态）、具有一致视觉反馈的同相双手运动[对称（Sym）状态]以及具有不一致视觉反馈的异相双手运动[不对称（Asy）状态]。我们发现，与静息状态相比，Sym状态下β振荡的降低幅度大于Asy状态，这表明在没有视觉冲突的情况下执行手部运动时M1的激活程度更高。功能连接模式的结果表明，在Asy状态下，V1与颞上回（STG）之间的α波段功能连接以及楔前叶与后扣带回皮层（PCC）之间的γ波段功能连接引发的相干强度比Sym状态下更大或略大。然而，在所有脑区对中，β波段功能连接在两种状态之间没有差异。这些发现证实并扩展了先前的研究结果，以提供证据表明镜像视觉反馈参与了与感知-注意力过程相关的功能网络并触发M1激活，尽管M1的激活在功能上独立于与运动功能无关的其他脑区。总之，本研究展示了面对视觉冲突时运动控制的具体功能连接模式，并为未来研究检查运动控制中镜像错觉的动态功能网络奠定了基础。
