微小RNA在胰腺癌中的作用
The Role of microRNA in Pancreatic Cancer.
作者信息
Smolarz Beata, Durczyński Adam, Romanowicz Hanna, Hogendorf Piotr
机构信息
Laboratory of Cancer Genetics, Department of Pathology, Polish Mother's Memorial Hospital Research Institute, 93-338 Lodz, Poland.
Department of General and Transplant Surgery, N. Barlicki Memorial Clinical Hospital, Medical University of Lodz, 90-153 Lodz, Poland.
出版信息
Biomedicines. 2021 Sep 26;9(10):1322. doi: 10.3390/biomedicines9101322.
Abstract
MicroRNAs (miRNAs) are small ribonucleic acid molecules that play a key role in regulating gene expression. The increasing number of studies undertaken on the functioning of microRNAs in the tumor formation clearly indicates their important potential in oncological therapy. Pancreatic cancer is one of the deadliest cancers. The expression of miRNAs released into the bloodstream appears to be a good indicator of progression and evaluation of the aggressiveness of pancreatic cancer, as indicated by studies. The work reviewed the latest literature on the importance of miRNAs for pancreatic cancer development.
摘要
微小RNA（miRNA）是一类小核糖核酸分子，在调节基因表达中起关键作用。对微小RNA在肿瘤形成过程中功能的研究越来越多，这清楚地表明了它们在肿瘤治疗中的重要潜力。胰腺癌是最致命的癌症之一。研究表明，释放到血液中的miRNA的表达似乎是胰腺癌进展和侵袭性评估的良好指标。这项工作回顾了关于miRNA对胰腺癌发展重要性的最新文献。
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