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用于胰腺癌诊断和治疗的分子靶点。

Molecular Targets for the Diagnosis and Treatment of Pancreatic Cancer.

机构信息

Department of Vascular Surgery, Englewood Health, Englewood, NJ 07631, USA.

Department of Surgical Oncology and HPB Surgery, Englewood Health, Englewood, NJ 07631, USA.

出版信息

Int J Mol Sci. 2024 Oct 9;25(19):10843. doi: 10.3390/ijms251910843.

Abstract

Pancreatic cancer is one of the most aggressive and lethal forms of cancer, with a five-year survival rate of less than 10%. Despite advances in treatment modalities, the prognosis for pancreatic cancer patients remains poor, highlighting the urgent need for innovative approaches for early diagnosis and targeted therapies. In recent years, there has been significant progress in understanding the molecular mechanisms underlying pancreatic cancer development and progression. This paper reviews the current knowledge of molecular targets for the diagnosis and treatment of pancreatic cancer.

摘要

胰腺癌是最具侵袭性和致命性的癌症之一,五年生存率不足 10%。尽管治疗方式有所进步,但胰腺癌患者的预后仍然较差,这突显了创新的早期诊断和靶向治疗方法的迫切需求。近年来,人们对胰腺癌发生和发展的分子机制有了更深入的了解。本文综述了目前用于胰腺癌诊断和治疗的分子靶点的相关知识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfb0/11476914/1e2fb3cf3fb5/ijms-25-10843-g001.jpg

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