一种[细菌名称]PW-7胞外多糖的抗菌活性。（注：原文中“Anti- Activity”表述有误，推测可能是“Antibacterial Activity”，这里按正确理解翻译）

Anti- Activity of a sp. PW-7 Exopolysaccharide.

作者信息

Hu Jingfei, Tian Xueqing, Wei Tong, Wu Hangjie, Lu Jing, Lyu Mingsheng, Wang Shujun

机构信息

Jiangsu Key Laboratory of Marine Bioresources and Environment, Jiangsu Key Laboratory of Marine Biotechnology, Jiangsu Ocean University, Lianyungang 222005, China.

Co-Innovation Center of Jiangsu Marine Bio-Industry Technology, Jiangsu Ocean University, Lianyungang 222005, China.

出版信息

Foods. 2021 Oct 14;10(10):2453. doi: 10.3390/foods10102453.

DOI:10.3390/foods10102453

PMID:34681500

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8535340/

Abstract

is a cause of gastric cancer. We extracted the exopolysaccharide (EPS) of PW-7 for antibacterial activity versus , elucidating its biological activity and structural characteristics. The minimum inhibitory concentration (MIC) of EPS against was 50 mg/mL. Disruption of the cell membranes of pathogenic bacteria by EPS was indicated via the antibacterial mechanism test and confirmed through electron microscopy. EPS also has antioxidant capacity. The IC of EPS for 2,2-Diphenyl-1-picrylhydrazyl (DPPH) radical, superoxide anions, and hydroxyl radicals were 300 μg/mL, 180 μg/mL, and 10 mg/mL, respectively. The reducing power of EPS was 2 mg/mL, equivalent to 20 μg/mL of ascorbic acid. EPS is a heteropolysaccharide comprising six monosaccharides, with an approximate molecular weight of 2.33 × 10 Da. Xylose had a significant effect on . EPS from PW-7 showed potential as an antibacterial compound and antioxidant, laying a foundation for the development of EPS-based foods.

摘要

是胃癌的一个病因。我们提取了PW - 7的胞外多糖（EPS）以检测其对……的抗菌活性，阐明其生物活性和结构特征。EPS对……的最低抑菌浓度（MIC）为50 mg/mL。通过抗菌机制测试表明EPS对病原菌细胞膜有破坏作用，并通过电子显微镜得到证实。EPS也具有抗氧化能力。EPS对2,2 - 二苯基 - 1 - 苦基肼（DPPH）自由基、超氧阴离子和羟基自由基的半数抑制浓度（IC）分别为300 μg/mL、180 μg/mL和10 mg/mL。EPS的还原力为2 mg/mL，相当于20 μg/mL的抗坏血酸。EPS是一种由六种单糖组成的杂多糖，分子量约为2.33×10 Da。木糖对……有显著影响。来自PW - 7的EPS显示出作为抗菌化合物和抗氧化剂的潜力，为基于EPS的食品开发奠定了基础。