Schwaberger Bernhard, Urlesberger Berndt, Schmölzer Georg M
Division of Neonatology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, 8036 Graz, Austria.
Centre for the Studies of Asphyxia and Resuscitation, Neonatal Research Unit, Royal Alexandra Hospital, Edmonton, AB T5H 3V9, Canada.
Children (Basel). 2021 Oct 2;8(10):882. doi: 10.3390/children8100882.
Premature infants born after less than 25 weeks' gestation are particularly vulnerable at birth and stabilization in the delivery room (DR) is challenging. After birth, infants born after <25 weeks' gestation develop respiratory and hemodynamic instability due to their immature physiology and anatomy. Successful stabilization at birth has the potential to reduce morbidities and mortalities, while suboptimal DR care could increase long-term sequelae. This article reviews current neonatal resuscitation guidelines and addresses challenges during DR stabilization in extremely premature infants born after <25 weeks' gestation at the threshold of viability.
妊娠少于25周出生的早产儿在出生时特别脆弱,在产房(DR)实现稳定状况具有挑战性。出生后,妊娠少于25周的婴儿因其生理和解剖结构不成熟而出现呼吸和血流动力学不稳定。出生时成功实现稳定状况有可能降低发病率和死亡率,而产房护理不佳可能会增加长期后遗症。本文回顾了当前的新生儿复苏指南,并探讨了妊娠少于25周、处于可存活临界值的极早产儿在产房稳定状况期间所面临的挑战。