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[供精宫腔内人工授精。治疗男性不育导致的不孕不育症]

[Intrauterine insemination with donor semen. Treatment of involuntary childlessness caused by male infertility].

作者信息

Vilsbøll T, Helmsøe-Zinck L, Andersen A N

机构信息

Fertilitetsklinikken, gynaekologisk obstetrisk afdeling G114, Amtssygehuset i Herlev.

出版信息

Ugeskr Laeger. 1994 Aug 22;156(34):4826-9.

PMID:7992417
Abstract

Intrauterine insemination with cryopreserved donor semen was performed in 114 women in a total of menstrual 381 cycles during the period 1.2.1991 to 15.5.1993. Eighty-one pregnancies were recorded corresponding to a conception rate of 21% per insemination cycle. After ten cycles the probability of conception and expected delivery was respectively 96% and 86%. The results show that intrauterine insemination with donor semen is a good treatment for couples with male infertility. Ultrasonic measurement of the follicles and timing of hCG injection were used for optimal timing of intrauterine donor insemination. The quality of the semen used for insemination is important. It is recommended to inseminate with at least two million of spermatozoa where at least 20% have normal motility.

摘要

1991年2月1日至1993年5月15日期间,114名女性共进行了381个月经周期的冷冻供精宫腔内人工授精。记录到81例妊娠,每个授精周期的受孕率为21%。十个周期后,受孕和预期分娩的概率分别为96%和86%。结果表明,供精宫腔内人工授精是治疗男性不育夫妇的一种有效方法。通过超声测量卵泡和注射人绒毛膜促性腺激素的时间来优化供精宫腔内人工授精的时机。用于授精的精液质量很重要。建议使用至少200万个精子进行授精,其中至少20%具有正常活力。

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