Department of Internal Medicine, University of Iowa, Iowa City, IA 52242, USA.
Department of Epidemiology, University of Iowa, Iowa City, IA 52242, USA.
Nutrients. 2021 Oct 5;13(10):3507. doi: 10.3390/nu13103507.
The low-saturated fat (Swank) and modified Paleolithic elimination (Wahls) diets have shown promise for MS symptoms; however, due to their restriction of specific foods, inadequate intake of micronutrients is concerning. Therefore, as part of a randomized trial, weighed food records were collected on three consecutive days and were used to evaluate the intake of micronutrients among people with relapsing remitting MS adapting these diets. After randomization to either the Swank or Wahls diets, diet education and support was provided by registered dietitians at baseline and throughout the first 12 weeks of the intervention. Usual intake of each micronutrient was estimated and then evaluated with the EAR-cut point method. At 12 weeks, the Swank group had significant reductions in the proportion with inadequate intake from food for vitamins C, D, and E, while the Wahls group had significant reductions for magnesium and vitamins A, C, D, and E. However, the proportion with inadequate intake significantly increased for calcium, thiamin, and vitamin B in the Wahls group and for vitamin A in the Swank group. Inclusion of intake from supplements reduced the proportion with inadequate intake for all micronutrients except calcium among the Wahls group but increased the proportion with excessive intake for vitamin D and niacin among both groups and magnesium among the Swank group. Both diets, especially when including intake from supplements, are associated with reduced inadequate intake compared to the normal diet of people with relapsing remitting MS.
低饱和脂肪(斯旺克)和改良旧石器时代消除(瓦尔)饮食法对多发性硬化症的症状有一定效果;然而,由于它们限制了特定的食物,微量营养素的摄入不足令人担忧。因此,作为一项随机试验的一部分,收集了连续三天的称重食物记录,用于评估适应这些饮食的复发缓解型多发性硬化症患者的微量营养素摄入情况。在随机分配到斯旺克或瓦尔饮食组后,营养师在基线和干预的前 12 周内提供饮食教育和支持。估计了每种微量营养素的通常摄入量,然后使用 EAR 切点法进行评估。在 12 周时,斯旺克组维生素 C、D 和 E 的食物摄入不足比例显著降低,而瓦尔组镁和维生素 A、C、D 和 E 的摄入不足比例显著降低。然而,瓦尔组钙、硫胺素和维生素 B 的摄入不足比例显著增加,斯旺克组维生素 A 的摄入不足比例显著增加。纳入补充剂的摄入量减少了除瓦尔组的钙以外的所有微量营养素摄入不足的比例,但增加了两组维生素 D 和烟酸以及斯旺克组镁摄入过量的比例。与复发缓解型多发性硬化症患者的正常饮食相比,这两种饮食法,特别是包括补充剂摄入量时,与减少微量营养素摄入不足有关。