Nafea Hajer, Abdelmegid Omnia, Qaddourah Sara, Abdulwahab Zainab, Moawad Joyce, Shi Zumin
Human Nutrition Department, College of Health Sciences, QU Health, Qatar University, Doha 2713, Qatar.
Nutrients. 2021 Oct 13;13(10):3580. doi: 10.3390/nu13103580.
The association between nuts intake and cognitive function is inconclusive. We aimed to investigate the association between habitual nuts consumption and cognition among Qatari adults. Data from 1000 participants aged >20 years who attended Qatar Biobank (QBB) were used. Nuts consumption was assessed by a food frequency questionnaire (FFQ). Blood samples were measured for magnesium, lipids and glucose. Mean reaction time (MRT) was used as an indicator of cognitive function. Linear regression was used to assess the association. A total of 21.1% of the participants reported consuming nuts ≥4-6 times/week (high consumption) while 40.2% reported consuming ≤1 time/month (low consumption). The mean MRT was 715.6 milliseconds (SD 204.1). An inverse association was found between nuts consumption and MRT. Compared to those with a low consumption, high consumption of nuts had a regression coefficient of -36.9 (95% CI -68.1 to -5.8) after adjusting for sociodemographic and lifestyle factors. The inverse association between nuts and MRT was mainly seen among those >50 years. There was an interaction between nuts consumption and hypertension. The association between nuts consumption and MRT was not mediated by hypertension, diabetes, or serum magnesium. Habitual higher consumption of nuts is positively associated with cognitive function, especially among old adults.
坚果摄入量与认知功能之间的关联尚无定论。我们旨在调查卡塔尔成年人习惯性食用坚果与认知之间的关联。使用了来自1000名年龄超过20岁且参加卡塔尔生物样本库(QBB)的参与者的数据。通过食物频率问卷(FFQ)评估坚果摄入量。对血液样本进行镁、脂质和葡萄糖检测。平均反应时间(MRT)用作认知功能指标。采用线性回归评估关联。共有21.1%的参与者报告每周食用坚果≥4 - 6次(高摄入量),而40.2%的参与者报告每月食用≤1次(低摄入量)。平均MRT为715.6毫秒(标准差204.1)。发现坚果摄入量与MRT呈负相关。在调整社会人口学和生活方式因素后,与低摄入量者相比,高坚果摄入量者的回归系数为 -36.9(95%置信区间 -68.1至 -5.8)。坚果与MRT之间的负相关主要见于年龄>50岁者。坚果摄入量与高血压之间存在交互作用。坚果摄入量与MRT之间的关联并非由高血压、糖尿病或血清镁介导。习惯性较高的坚果摄入量与认知功能呈正相关,尤其是在老年人中。